Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Green coffee, green tea, cumin, and mustard contain potentially bioaccessible TPO activators that also act as effective LOX inhibitors, which indicate their potentially health-promoting effects for people suffering from Hashimoto's disease.
|
31671724 |
2019 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
A diagnosis of autoimmune thyroiditis (AT) in thyrotoxic phase was made on the basis of clinical presentation and presence of anti-TPO antibodies and reduced uptake in thyroid (technetium) scintigraphy.
|
30128632 |
2019 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Conclusions Fluctuating thyroid function tests in addition to thyroid peroxidase antibody (TPO Ab) positivity complicated the diagnosis of RTH, initially diagnosed as Hashimoto's thyroiditis.
|
30681972 |
2019 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our key and novel finding is the existence of significant positive correlation between TgAb levels and the number of symptoms (r = 0.25, p = 0.0001) in HT patients without LT4 therapy that remained significant after adjustment for TPOAb, T3, TSH levels and thyroid volume (β = 0.66, SE = 0.3, p = 0.0299).
|
30332318 |
2019 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Autoimmunity to TPO is characterised by autoantibodies and T cell reactivity in Hashimoto's disease and Graves' disease.
|
30742860 |
2019 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
This study included 933 patients with thyroid peroxidase antibodies (anti-TPO-Ab) ≥34 kIU/l, including most patients with clear AIT due to a concurrent sonographic evidence of reduced echogenicity.
|
31766063 |
2019 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Antibodies to thyroid peroxidase (TPO), the enzyme that catalyses thyroid-hormone production and antibodies to the receptor for the thyroid-stimulating hormone, are characteristic of HT and GD, respectively.
|
30208979 |
2019 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
The prevalence of anti thyroperoxidase (TPO) was significantly increased in the autoimmune thyroiditis (AIT).
|
30807792 |
2019 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Thyroid dysfunction (TD) is caused by thyroid peroxidase (TPO) antibody, as seen in Hashimoto's disease.
|
31776300 |
2019 |
Hashimoto Disease
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
This clinical trial was designed to investigate the impact of Se and vitamin C supplementation on antithyroid peroxidase antibody (TPO-Ab) level in patients with AIT.
|
30182359 |
2019 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Thyroid antibodies against thyroglobulin (TgAb) and thyroid peroxidase (TPOAb) are key markers of Hashimoto's thyroiditis (HT), the most common autoimmune thyroid disorder.
|
30926877 |
2019 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
In those with HT, MMP-3 correlated negatively with FT3 (rho=-0.545, P=0.048) and positively with TPO-Ab and HI (rho=0.735, P=0.02; rho=0.769, P=0.01, respectively).
|
29442475 |
2018 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
The aim of the present study was to explore the effect of Se on thyroid peroxidase antibody (TPOAb) titers in patients with AIT and to analyze a potential impact of the genetic background on the effect of Se supplementation Methods Randomized, placebo-controlled, double-blind trial.
|
30398407 |
2018 |
Hashimoto Disease
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Most importantly, only Tfh17 cell percentages were positively correlated with anti-thyroglobulin and anti-thyroid peroxidase antibody levels and were negatively correlated serum free T3 and free T4 levels in HT patients.
|
30345813 |
2018 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Thyroid Peroxidase as an Autoantigen in Hashimoto's Disease: Structure, Function, and Antigenicity.
|
30360003 |
2018 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
We identified all studies that assessed the changes of TPO-Ab and Tg-Ab in patients with AIT under the treatment of vitamin D from PubMed, Embase, The Cochrane Library, Chinese National Knowledge Infrastructure, Wanfang, and VIP Database.
|
29388046 |
2018 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
To study the prevalence of Hashimoto thyroiditis (HT), anti-thyroid autoantibodies (anti-thyroglobulin or TgAb and thyroperoxidase or TPOAb) in systemic lupus erythematosus (SLE) patients.
|
28544477 |
2018 |
Hashimoto Disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We experienced a 6-year-old case of drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) with subsequent development autoimmune thyroiditis (Hashimoto's thyroiditis), type 1 diabetes with antithyroglobulin, thyroid peroxidase, insulinoma-associated antigen and anti-insulin antibodies at 4 months, alopecia at 7 months, vitiligo, uveitis due to Vogt-Koyanagi-Harada disease at 8 months after clinical resolution of the DiHS/DRESS.
|
30368475 |
2018 |
Hashimoto Disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to evaluate cognitive function and quality of life (QoL) in patients on long-term levothyroxine replacement for HT in relation to thyroid function tests and TPO (thyroid-peroxidase) antibody (TPOAb) status.
|
29959689 |
2018 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
The percentage positive for thyroid peroxidase (TPO) antibody and lymphocytic thyroiditis was significantly higher in the TgAb-positive group.
|
28493284 |
2017 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
In our study, prevalence of TPO-Ab positivity is more frequent in subjects with <i>H. pylori</i> infection.Our findings suggest <i>H. pylori</i> infection may play a role in the development of autoimmune thyroiditis.
|
28092700 |
2017 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Only data from patients with laboratory-confirmed HT (anti-thyroid peroxidase [anti-TPO] antibodies; thyroglobulin antibodies; serum thyroid-stimulating hormone; and free T3) were eligible for inclusion.
|
28217937 |
2017 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
In FNAC studies, the association between HT and PTC is based on the comparison of anti-thyroid autoantibodies (ATA) (anti-thyroperoxidase [TPOAb] and anti-thyroglobulin [TgAb]), thyroid function (TSH), and cytology with histology of thyroid nodules and lymphocytic thyroid infiltration (LTI) of operated thyroid glands.
|
28868258 |
2017 |
Hashimoto Disease
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The procalcitonin and anti-thyroid peroxidase levels were identified to be an independent predictor in diagnosis of Hashimoto's thyroiditis.
|
28171686 |
2017 |
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Instead, our finding that low dietary Se potentiates the development of autoantibodies to Tg and TPO in females is consistent with reports in humans of an increased prevalence of autoimmune thyroiditis in low-Se regions.
|
28938453 |
2017 |