TRAF3, TNF receptor associated factor 3, 7187

N. diseases: 129; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma
0.030 Biomarker disease BEFREE Signaling mechanisms of bortezomib in TRAF3-deficient mouse B lymphoma and human multiple myeloma cells. 26740054 2016
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma
0.030 Biomarker disease BEFREE In vitro anti-tumor activities of AD 198 and PEP005 were determined using TRAF3-/- mouse B lymphoma and human patient-derived MM cell lines as model systems. 24131623 2013
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma
0.030 AlteredExpression disease BEFREE Together, these data indicate that a number of TRAF-3 splice-variant mRNAs are expressed and function in B and T lymphoma lines, which suggests that certain TRAF-3 splice-variant isoforms may participate in mediating the known functions of the TRAF-3 gene in lymphocytes. 11600226 2001