TRH, thyrotropin releasing hormone, 7200

N. diseases: 230; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002622
Disease: Amnesia
Amnesia
0.300 Therapeutic disease CTD_human In addition, coadministration of JTP-4819 and substance P, arginine-vasopressin or thyrotropin-releasing hormone (at doses at which each drug alone did not prolong the retention time) improved the retention time of rats with scopolamine-induced amnesia. 7562510 1995
CUI: C0002622
Disease: Amnesia
Amnesia
0.300 Therapeutic disease CTD_human NS-3 improved amnesia caused by scopolamine, electroconvulsive shock (ECS), and cycloheximide (CXM), but TRH improved only the ECS-induced amnesia. 7617693 1995
CUI: C0002622
Disease: Amnesia
Amnesia
0.300 Therapeutic disease CTD_human Repeated administration of TRH for 7 days at doses of 0.2-5 mg/kg s.c. elicited a dose-dependent recovery from amnesia induced by scopolamine, whereas only the group treated with 5 mg/kg/day showed a significant improvement. 8405091 1993