TRH, thyrotropin releasing hormone, 7200

N. diseases: 230; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.330 Biomarker disease PSYGENET These results suggest that in male mice GHRH deficiency brings about an increased physical activity and decreased anxiety- and depression-related behaviour, possibly related to increased TRH and decreased NE levels in the brain. 25028079 2014
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.330 Biomarker disease PSYGENET Female, but not male, TRH-R2 knockout mice exhibit moderately increased depression-like and reduced anxiety-like phenotypes. 19078951 2009
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.330 Biomarker disease BEFREE The early-onset dysthymics showed a higher number of persons who had never married, who presented a more traumatic and frustrating childhood background, and who had a higher rate of DST non-suppressors and blunted TSH responses after TRH administration during the period of their double depression. 7798461 1994
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.330 Biomarker disease PSYGENET The early-onset dysthymics showed a higher number of persons who had never married, who presented a more traumatic and frustrating childhood background, and who had a higher rate of DST non-suppressors and blunted TSH responses after TRH administration during the period of their double depression. 7798461 1994
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.330 Biomarker disease PSYGENET The results of the TRH test and the DST point to similar endocrinological patterns in alcoholics as in depressive patients and thus support the hypothesis of a link between alcoholism and depression. 2543997 1989
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.330 Biomarker disease BEFREE The results of the TRH test and the DST point to similar endocrinological patterns in alcoholics as in depressive patients and thus support the hypothesis of a link between alcoholism and depression. 2543997 1989
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.330 Biomarker disease BEFREE Neither the DST nor TRH test was found to distinguish significantly among the four familial subgroups of depression. 6412261 1983
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.330 Biomarker disease PSYGENET Neither the DST nor TRH test was found to distinguish significantly among the four familial subgroups of depression. 6412261 1983