Hypothyroidism
|
0.410 |
AlteredExpression
|
disease |
BEFREE |
Taken together, p38/TRHr-dependent regulation of TPO in thyroid cells contributes to the hypothyroidism of triclosan-treated rats.
|
29462796 |
2018 |
Hypothyroidism
|
0.410 |
Biomarker
|
disease |
CTD_human |
A novel mechanism for isolated central hypothyroidism: inactivating mutations in the thyrotropin-releasing hormone receptor gene.
|
9141550 |
1997 |
Hypothyroidism
|
0.410 |
Biomarker
|
disease |
HPO |
|
|
|
Central hypothyroidism
|
0.310 |
GeneticVariation
|
disease |
BEFREE |
Central Hypothyroidism Due to a TRHR Mutation Causing Impaired Ligand Affinity and Transactivation of Gq.
|
28419241 |
2017 |
Central hypothyroidism
|
0.310 |
Biomarker
|
disease |
CTD_human |
A novel mechanism for isolated central hypothyroidism: inactivating mutations in the thyrotropin-releasing hormone receptor gene.
|
9141550 |
1997 |
Congenital central hypothyroidism due to thyrotropin-releasing hormone receptor deficiency
|
0.300 |
GermlineCausalMutation
|
disease |
ORPHANET |
Clinical review: Central hypothyroidism: pathogenic, diagnostic, and therapeutic challenges.
|
22851492 |
2012 |
Congenital central hypothyroidism due to thyrotropin-releasing hormone receptor deficiency
|
0.300 |
GermlineCausalMutation
|
disease |
ORPHANET |
Congenital hypothyroidism.
|
20537182 |
2010 |
Thyrotropin-Releasing Hormone Resistance, Generalized
|
0.300 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
A family with complete resistance to thyrotropin-releasing hormone.
|
19213692 |
2009 |
Thyroid Hormone Resistance Syndrome
|
0.300 |
Biomarker
|
disease |
CTD_human |
A novel mechanism for isolated central hypothyroidism: inactivating mutations in the thyrotropin-releasing hormone receptor gene.
|
9141550 |
1997 |
Secondary hypothyroidism
|
0.300 |
Biomarker
|
disease |
CTD_human |
A novel mechanism for isolated central hypothyroidism: inactivating mutations in the thyrotropin-releasing hormone receptor gene.
|
9141550 |
1997 |
Primary Hypothyroidism
|
0.300 |
Biomarker
|
disease |
CTD_human |
A novel mechanism for isolated central hypothyroidism: inactivating mutations in the thyrotropin-releasing hormone receptor gene.
|
9141550 |
1997 |
Generalized Thyroid Hormone Resistance
|
0.300 |
Biomarker
|
disease |
CTD_human |
A novel mechanism for isolated central hypothyroidism: inactivating mutations in the thyrotropin-releasing hormone receptor gene.
|
9141550 |
1997 |
Congenital Hypothyroidism
|
0.210 |
GeneticVariation
|
disease |
BEFREE |
A Novel Thyrotropin-Releasing Hormone Receptor Missense Mutation (P81R) in Central Congenital Hypothyroidism.
|
26735259 |
2016 |
Hypertensive disease
|
0.210 |
Biomarker
|
group |
BEFREE |
As it has been demonstrated that hypertensive patients have a blunted TSH response to TRH injection, suggesting a defect in the TRHR, we postulate that the TRHR gene is involved in human hypertension.
|
11566956 |
2001 |
Hypertensive disease
|
0.210 |
Biomarker
|
group |
RGD |
Antisense to thyrotropin releasing hormone receptor reduces arterial blood pressure in spontaneously hypertensive rats.
|
7554113 |
1995 |
Congenital Hypothyroidism
|
0.210 |
Biomarker
|
disease |
MGD |
|
|
|
Endemic Cretinism
|
0.200 |
Biomarker
|
disease |
MGD |
|
|
|
White Blood Cell Count procedure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Lean body mass
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Genome-wide association and replication studies identified TRHR as an important gene for lean body mass.
|
19268274 |
2009 |
Lean body mass
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association and replication studies identified TRHR as an important gene for lean body mass.
|
19268274 |
2009 |
Constipation
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Macroglossia
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
Sleep disturbances
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Feeding difficulties
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Growth delay
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|