|
Cardiovascular Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
β-actin (ACTB) participates in the vascular remodeling and contributes to the cardiovascular diseases.
|
31327802 |
2020 |
|
Bacterial Infections
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Evaluation of the expression stability of β-actin under bacterial infection in Macrobrachium nipponense.
|
30515694 |
2019 |
|
Developmental Disabilities
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Beta-actin (ACTB) loss-of-function mutations result in a pleiotropic developmental disorder of kidney.
|
31396261 |
2019 |
|
Encephalomyelitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Abbreviations: 3-MA: 3-methylademine; ACTB/β-actin: actin, beta; ATG: autophagy related; ATG16L1: autophagy related 16-like 1 (S. cerevisiae); BECN1: beclin 1, autophagy related; CNR2: cannabinoid receptor 2 (macrophage); CNS: central nervous system; CQ: chloroquine; EAE: experimental autoimmune encephalomyelitis; FOXO3: forkhead box O3; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; H&E: hematoxylin and eosin; ITGAM: integrin alpha M; LPS: lipoplysaccharide; MAP1LC3/LC3: microtubule-associated protein 1 light chain 3; miRNAs: microRNAs; MS: multiple sclerosis; PPARG: peroxisome proliferator activated receptor gamma; PTPRC: protein tyrosine phosphatase, receptor type, C; RA: rheumatoid arthritis; SQSTM1: sequestosome 1; TB: tuberculosis; TIMM23: translocase of inner mitochondrial membrane 23; TLR: toll-like receptor.
|
30208760 |
2019 |
|
Hand, Foot and Mouth Disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
In summary, Our results showed that SAA and human β-actin (ACTB) may be served as a potential biomarker of the clinical diagnosis of severe HFMD.
|
30817906 |
2019 |
|
Lupus Nephritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Lupus nephritis (class IV) had higher STAT3/β-actin intensity than SLE without renal involvement.
|
30767092 |
2019 |
|
Neoplasm Metastasis
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Lentivirus-mediated shRNA knockdown of SEPT9 in MCF-7 cells diminished tumor cell migration, focal adhesion (FA) maturation and the expression of β-actin, β-tubulin, Cdc42, RhoA, and Rac, whereas overexpression of SEPT9_i1 in SEPT9-knockdown MCF-7 cells promoted cell migration, FA maturation and relevant protein expression.
|
31558699 |
2019 |
|
Neurilemmoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
However, we did not observe any significant difference between the activity of the CBA and P0 promoters in a xenograft schwannoma model.
|
31125589 |
2019 |
|
Pancreatic Neoplasm
|
0.010 |
Biomarker
|
disease |
BEFREE |
When CAG-CAT-MitoTimer mice were crossbred with various tissue-specific (muscle, adipose tissue, kidney, and pancreatic tumor) or global Cre transgenic mice, the double transgenic offspring showed MitoTimer expression in tissue-specific or global manner.
|
29274400 |
2019 |
|
Fibrosis, Liver
|
0.010 |
Biomarker
|
disease |
BEFREE |
This study provides evidences that β-actin is variable and unsatisfied for application as an internal control in hepatic fibrosis induced by <i>S. japonicum</i> infection.
|
30766520 |
2019 |
|
Intellectual Disability
|
0.010 |
Biomarker
|
group |
BEFREE |
The lipid peroxidation of PBMC and RBC membranes, levels of serum glutamate, serotonin, homocysteine, ROS, lactate and LDH-A expression increased significantly with severity of ID whereas changes in RBC membrane β-actin, serum BDNF, TNF-α and IL-6 was found non-significant.
|
31541143 |
2019 |
|
Arteriosclerosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The microdevice was successfully implemented for the identification of the β-actin gene, a constitutively expressed gene in all cells, and the sphingosine-1-phosphate lyase 1 gene, a potential pharmacological target gene in the diagnosis of cancer, diabetes, and atherosclerosis.
|
30318528 |
2018 |
|
Atherosclerosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The microdevice was successfully implemented for the identification of the β-actin gene, a constitutively expressed gene in all cells, and the sphingosine-1-phosphate lyase 1 gene, a potential pharmacological target gene in the diagnosis of cancer, diabetes, and atherosclerosis.
|
30318528 |
2018 |
|
Cerebral Infarction
|
0.010 |
Biomarker
|
disease |
BEFREE |
We concluded that β-actin is likely cleaved by granzyme B by 24 hours following 10-minute and 2-hour focal cerebral ischemia.
|
29408985 |
2018 |
|
Squamous cell carcinoma of esophagus
|
0.010 |
Biomarker
|
disease |
BEFREE |
Copies of HPV16 E2, E6, and the human housekeeping gene β-actin were tested using quantitative PCR to analyze the relationship between HPV16 integration and esophageal squamous cell carcinoma and the relationship between the HPV16 integration status and clinical information of patients.
|
29749321 |
2018 |
|
Skin callus
|
0.010 |
Biomarker
|
disease |
BEFREE |
In this study, 13 candidate reference genes, including 12 novel putative reference genes selected from a large set of S. album transcriptome data, as well as the currently used β-actin gene (ACT), were validated in different tissues (stem, leaf, root and callus), as well as callus tissue under salicylic acid (SA), jasmonic acid methyl ester (MeJA), and gibberellin (GA) treatments using geNorm, NormFinder, BestKeeper, Delta Ct and comprehensive RefFinder algorithms.
|
30504917 |
2018 |
|
Middle Cerebral Artery Occlusion
|
0.010 |
Biomarker
|
disease |
BEFREE |
The results revealed that HPRT and 18S were the most stable reference genes in the cortices of MCAO mice and that β-actin and cyclophilin were the most stable reference genes in the OGD/R-injured N2a cells; in contrast, GAPDH and Sdha were the least stable genes in the cortices of MCAO mice and the OGD/R-injured N2a cells, respectively.
|
29390963 |
2018 |
|
SPINAL MUSCULAR ATROPHY WITH RESPIRATORY DISTRESS 1
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Impaired Local Translation of β-actin mRNA in Ighmbp2-Deficient Motoneurons: Implications for Spinal Muscular Atrophy with respiratory Distress (SMARD1).
|
29928949 |
2018 |
|
Malignant tumor of colon
|
0.010 |
Biomarker
|
disease |
BEFREE |
We have showed that three traditional internal reference genes, β-actin, GAPDH and α-tubulin, are not suitable for studying gene transcription in colon cancer cells treated with aspirin, and we have identified and validated TMEM208 and PQLC2 as the ideal internal reference genes for detecting the molecular targets of aspirin in colon cancer in vitro and in vivo.
|
28184026 |
2017 |
|
Dermatomyositis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
However, the expression of β-actin is significantly increased in DM and sIBM in consistence with muscle and fiber regeneration.
|
28183315 |
2017 |
|
Hyperglycemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Matrix-assisted laser desorption/ionization-time of flight/tandem mass spectrometry identified 30 Lys63-ubiquitinated proteins, mainly involved in cellular organization, such as β-actin, whose Lys63 ubiquitination increased under HG, leading to cytoskeleton disorganization.
|
27881486 |
2017 |
|
Malaria, Cerebral
|
0.010 |
Biomarker
|
disease |
BEFREE |
Furthermore, these observations correlated with diminished protein levels of LIMK-1, cofilin-1, phospho-cofilin-1, and β-actin in the whole brain lysates as well as formation of actin-cofilin rods in the brain sections of symptomatic mice with CM.
|
28843047 |
2017 |
|
Tracheal Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
These results suggest that AAV6-CAG vectors are more promising than the previously preferred AAV2 vectors for airway transduction, particularly when administered into the trachea.
|
28346434 |
2017 |
|
Adenocarcinoma of lung (disorder)
|
0.010 |
Biomarker
|
disease |
BEFREE |
These results demonstrate the indispensable role of Fe-S clusters when ABCE1 participates in the proliferation and migration of LUADs by interacting with β-actin.
|
29145194 |
2017 |
|
Adult type dermatomyositis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
However, the expression of β-actin is significantly increased in DM and sIBM in consistence with muscle and fiber regeneration.
|
28183315 |
2017 |