TNFSF4, TNF superfamily member 4, 7292

N. diseases: 129; N. variants: 32
Disease: Myocardial Infarction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.400 GeneticVariation disease BEFREE In conclusion, this case-control study confirms that the rs3850641 polymorphism of the TNFSF4 gene increases the risk of MI. 29921578 2018
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.400 GeneticVariation disease BEFREE Our study showed that the A allele of the rs7518045 and haplotype rs3861950C-rs17346501C-rs7518045A-rs1234313G in the TNFSF4 gene were associated with decreased MI risk in a Chinese Han population. 26125814 2015
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.400 GeneticVariation disease BEFREE Recent studies indicate that the single nucleotide polymorphism (SNP) rs3850641 in TNFSF4 is associated with higher risk of myocardial infarction, but little is known about the association between TNFSF4 variation and cerebral infarction (CI). 23184501 2013
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.400 GeneticVariation disease BEFREE Our data indicate that the TNFSF4 rs45454293T-allele is associated with lower TNFSF4 expression and increased risk of MI. 21445270 2011
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.400 GeneticVariation disease BEFREE Our study examined 235 patients with acute coronary syndrome (ACS) and 220 controls and sought to establish whether polymorphisms in OX40/OX40L are associated with atherosclerosis or myocardial infarction in the Han Chinese population. 21476935 2011
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.400 GeneticVariation disease BEFREE In two independent human cohorts, the minor allele of SNP rs3850641 in TNFSF4 was significantly more frequent in individuals with myocardial infarction than in controls. 18998106 2009
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.400 Biomarker disease BEFREE Moreover, association of the TNFRSF4 and TNFSF4 (tumor necrosis factor (ligand) superfamily, member 4) genes with myocardial infarction was recently reported. 18398332 2008
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.400 GeneticVariation disease BEFREE Recent data have implicated tumor necrosis factor (ligand) superfamily, member 4 (TNFSF4) gene variation in myocardial infarction in women; however, no prospective data are available on either incident arterial or venous disorders. 18356244 2008
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.400 Biomarker disease BEFREE Polymorphisms in myocyte enhancer factor 2A, a transcription factor, tumor necrosis factor (ligand) superfamily, member 4, the OX40 ligand, and proprotein convertase subtilisin/kexin type 9, which affect low-density lipoprotein levels, have all been associated with an altered risk of coronary artery disease and myocardial infarction. 16943719 2006
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.400 GeneticVariation disease BEFREE We recently showed that genetic variants in OX40L are associated with myocardial infarction (MI) and severity of coronary artery disease in human. 16329997 2006
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.400 GeneticVariation disease BEFREE We therefore conclude that Tnfsf4 underlies Ath1 in mice and that polymorphisms in its human homolog TNFSF4 increase the risk of myocardial infarction in humans. 15750594 2005
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.400 Biomarker disease CTD_human