CCR2, C-C motif chemokine receptor 2, 729230

N. diseases: 436; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3714636
Disease: Pneumonitis
Pneumonitis
0.320 AlteredExpression disease BEFREE Importantly, dysregulation is observed as a chronic inflammation, which can progress into pneumonitis and promote pulmonary fibrosis; inflammatory monocytes, which are bone marrow derived and express CCR2, have been shown to migrate into the lung after radiation exposure. 29332538 2018
CUI: C3714636
Disease: Pneumonitis
Pneumonitis
0.320 Biomarker disease BEFREE Lung inflammation in tissue from subjects with nondiseased lungs donated for lung transplantation (n = 11) and those with chronic obstructive pulmonary disease (COPD) who were undergoing lung transplantation (n = 16) was evaluated for CCR2 with immunostaining and autoradiography (n = 6, COPD) with <sup>64</sup>Cu-DOTA-ECL1i. 28045644 2017
CUI: C3714636
Disease: Pneumonitis
Pneumonitis
0.320 Biomarker disease CTD_human Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression. 21625544 2011