TYMS, thymidylate synthetase, 7298

N. diseases: 406; N. variants: 19
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002871
Disease: Anemia
Anemia
0.320 GeneticVariation disease BEFREE MTHFR 677C>T also increased the risk of leukopenia and gastrointestinal toxicity, whilst thymidylate synthase 28 bp repeat polymorphism increased the risk of anemia (odds ratio 8.48, 95% confidence interval 2.00-36.09). 19648163 2009
CUI: C0002871
Disease: Anemia
Anemia
0.320 Biomarker disease CTD_human MTHFR 677C>T also increased the risk of leukopenia and gastrointestinal toxicity, whilst thymidylate synthase 28 bp repeat polymorphism increased the risk of anemia (odds ratio 8.48, 95% confidence interval 2.00-36.09). 19648163 2009
CUI: C0002871
Disease: Anemia
Anemia
0.320 GeneticVariation disease BEFREE The VNTR in the TYMS appears to be a predictive factor for anemia and thrombocytopenia in patients treated with this regimen. 25294632 2014