TYMS, thymidylate synthetase, 7298

N. diseases: 406; N. variants: 19
Disease: Lymphoma, Follicular ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024301
Disease: Lymphoma, Follicular
Lymphoma, Follicular 		0.320 GeneticVariation disease BEFREE Individuals with MTR 2756AA had 2-fold higher risk of FL, and subjects not having at least one TYMS 2R allele showed a 2-fold higher risk of FL. 16410450 2006
CUI: C0024301
Disease: Lymphoma, Follicular
Lymphoma, Follicular 		0.320 Biomarker disease CTD_human Individuals with MTR 2756AA had 2-fold higher risk of FL, and subjects not having at least one TYMS 2R allele showed a 2-fold higher risk of FL. 16410450 2006
CUI: C0024301
Disease: Lymphoma, Follicular
Lymphoma, Follicular 		0.320 GeneticVariation disease BEFREE Marginal increased risks were also observed for diffuse large B cell lymphoma with the TYMS homozygous 6 bp deletion (OR, 1.61; 95% CI, 0.99-2.60) and for follicular lymphoma with RFC 80AA (OR, 1.44; 95% CI, 0.94-2.22) and TYMS 28-bp repeat 2R/3R (OR, 1.45; 95% CI, 0.96-2.2). 16365025 2005