Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.070 Biomarker disease BEFREE Liver function tests (alanine aminotransferase, ALT; gamma-glutamyltransferase, GGT) not always normalize after elimination of hepatitis C virus (HCV) by direct acting antivirals (DAAs), possibly indicating concomitant non-viral liver diseases. 31241820 2020
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.070 GeneticVariation disease BEFREE DBP polymorphism was associated to HCV genotype (GC rs7041), previous HCV treatment, and GGT (GC rs4588).In conclusion, low frequency of vitamin D deficiency was found, but VDR polymorphisms were frequently associated to fibrosis grade suggesting that they could be used as disease evaluation markers to understand the mechanisms underlying the virus-host interaction. 29465575 2018
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.070 Biomarker disease BEFREE The changes in the ALT, GGT, HDL, INR, Alb and AFP levels in the patients with HCV-induced cirrhosis and HCV-related HCC were statistically significant. 29286922 2018
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.070 GeneticVariation disease BEFREE Samples collected from HCV (n = 74) and HBV (n = 35) carriers were subjected to quantitative real-time PCR (qPCR) to detect the presence of the SNPs rs5743305 and rs3775291 in TLR3 and to measure the following biomarkers: alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transpeptidase (GGT), and prothrombin time (PT). 25992926 2016
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.070 Biomarker disease BEFREE A significant correlation was found between the IFNL3 polymorphisms and biochemical as well as virologic predictors of treatment outcome such as ALT, GGT, cholesterol, and HCV RNA levels. 24204859 2013
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.070 Biomarker disease BEFREE Anti-Golgi antibody was positive during treatment coinciding with ALT/GGT flares but with hepatitis C virus (HCV)-RNA negativity, disappearing after stopping treatment, with normalization of ALT/AST levels. 17032416 2006
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.070 AlteredExpression disease BEFREE Traditional tests of liver function (ALT, AST, AP, and GGT) were of limited use in predicting HCV-RNA transmission. 8154029 1994