TYR, tyrosinase, 7299

N. diseases: 281; N. variants: 121
Disease: Malignant neoplasm of skin ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007114
Disease: Malignant neoplasm of skin
Malignant neoplasm of skin 		0.320 GeneticVariation disease BEFREE Our data confirmed the association of TYR p.R402Q with SK risk in the French population, and support that rare deleterious TYR variants may also play a role in multi-factorial genetic predisposition to SK. 21906913 2011
CUI: C0007114
Disease: Malignant neoplasm of skin
Malignant neoplasm of skin 		0.320 GeneticVariation disease BEFREE Hence, rare variants in TYR may be important risk factors for skin cancer. 19320745 2009
CUI: C0007114
Disease: Malignant neoplasm of skin
Malignant neoplasm of skin 		0.320 Biomarker disease CTD_human ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma. 18488027 2008