TYR, tyrosinase, 7299

N. diseases: 281; N. variants: 121
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.340 Biomarker disease BEFREE The 4th gene, tyrosinase, has been previously linked to schizophrenia through the cosegregation of oculocutaneous albinism with psychosis in several pedigrees. 11352574 2001
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.340 Biomarker disease PSYGENET The 4th gene, tyrosinase, has been previously linked to schizophrenia through the cosegregation of oculocutaneous albinism with psychosis in several pedigrees. 11352574 2001
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.340 Biomarker disease BEFREE In addition, the dopamine D2 receptor, porphobilinogen deaminase, and tyrosinase genes map within the region studied and may be aetiologically involved in schizophrenia. 8475213 1993
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.340 GeneticVariation disease BEFREE Genetic linkage, molecular analysis, and in situ hybridization have identified TYR and D11S388 as markers flanking the chromosome 11 breakpoint in a large pedigree where a balanced translocation, t(1;11)(q43;q21), segregates with schizophrenia and related affective disorders. 8383424 1993
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.340 GeneticVariation disease BEFREE Recent reports of cytogenetic abnormalities linked to psychiatric illness and the localisations of the genes for the dopamine (D2) receptor and tyrosinase on the long arm of chromosome 11 have suggested that susceptibility loci for schizophrenia and manic depression might be situated in this region. 1677600 1991