UBE2I, ubiquitin conjugating enzyme E2 I, 7329

N. diseases: 131; N. variants: 7
Disease: Breast Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.090 Biomarker disease BEFREE In this study, we used nine antitumor agents with distinct actions to explore Ubc9-mediated resistance in human breast carcinoma MCF-7 cells. 27878232 2017
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.090 Biomarker disease BEFREE Collectively, these data provide evidence that P18 may represent a promising therapeutic strategy for the inhibition of growth and progression of breast cancer and p53-miR-34a axis is important for P18 function. 27259808 2016
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.090 Biomarker disease BEFREE Breast cancer susceptibility gene 1, MMSET and UBC9 can be useful for customising chemotherapy in gastric cancer patients. 24809779 2014
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.090 Biomarker disease BEFREE Our results suggest that the variability of the UBC9 gene can play a role in breast cancer occurrence. 23873416 2014
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.090 GeneticVariation disease BEFREE We also found statistically significant (p<0.05) difference in DRE related to the c.73G>A polymorphism of the UBC9 gene in breast cancer patients. 20863840 2010
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.090 Biomarker disease BEFREE We have earlier reported that Ubc9 promotes tumor growth in the xenograft mouse model using breast cancer cell line MCF-7 in part through regulation of Bcl-2 expression. 20023705 2010
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.090 GeneticVariation disease BEFREE Polymorphisms in the UBC9 and PIAS3 genes of the SUMO-conjugating system and breast cancer risk. 19760037 2010
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.090 GeneticVariation disease BEFREE The present results underline the value of genetic variation in UBC9 for breast cancer prognosis. 19358266 2009
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.090 GeneticVariation disease BEFREE Structure of the gene encoding the human cyclin-dependent kinase inhibitor p18 and mutational analysis in breast cancer. 9636670 1998