OROFACIAL CLEFT 10
|
0.500 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Investigation of SUMO pathway genes in the etiology of nonsyndromic cleft lip with or without cleft palate.
|
22492558 |
2012 |
OROFACIAL CLEFT 10
|
0.500 |
Biomarker
|
disease |
CTD_human |
|
|
|
Hypodontia
|
0.400 |
GeneticVariation
|
disease |
ORPHANET |
|
|
|
Hypodontia
|
0.400 |
Biomarker
|
disease |
HPO |
|
|
|
Oligodontia
|
0.400 |
Biomarker
|
disease |
HPO |
|
|
|
Oligodontia
|
0.400 |
GeneticVariation
|
disease |
ORPHANET |
|
|
|
Cleft Lip with or without Cleft Palate
|
0.340 |
Biomarker
|
disease |
BEFREE |
SUMO1 has been implicated as having a role in the causation of cleft lip with or without cleft palate (CLP), both directly and through association studies in humans and, perhaps more controversially, in transgenic mouse studies.
|
22492558 |
2012 |
Cleft Lip with or without Cleft Palate
|
0.340 |
Biomarker
|
disease |
BEFREE |
SUMO1 as a candidate gene for non-syndromic cleft lip with or without cleft palate: no evidence for the involvement of common or rare variants in Central European patients.
|
21044801 |
2011 |
Cleft Lip with or without Cleft Palate
|
0.340 |
GeneticVariation
|
disease |
BEFREE |
SUMO1 polymorphisms are associated with non-syndromic cleft lip with or without cleft palate.
|
18983974 |
2008 |
Cleft Lip with or without Cleft Palate
|
0.340 |
Biomarker
|
disease |
BEFREE |
The risk factors identified in this study may provide a better understanding of the etiological role of SUMO1 in nonsyndromic cleft lip with or without cleft palate incidence.
|
20738159 |
2010 |
Cleft Lip with or without Cleft Palate
|
0.340 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
SUMO1 has been implicated as having a role in the causation of cleft lip with or without cleft palate (CLP), both directly and through association studies in humans and, perhaps more controversially, in transgenic mouse studies.
|
22492558 |
2012 |
Cleft upper lip
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
SUMO1 genetic polymorphisms may contribute to the risk of nonsyndromic cleft lip with or without palate: a meta-analysis.
|
25111678 |
2014 |
Cleft upper lip
|
0.320 |
GeneticVariation
|
disease |
LHGDN |
SUMO1 polymorphisms are associated with non-syndromic cleft lip with or without cleft palate.
|
18983974 |
2008 |
Cleft upper lip
|
0.320 |
Biomarker
|
disease |
CTD_human |
SUMO1 haploinsufficiency leads to cleft lip and palate.
|
16990542 |
2006 |
Cleft Palate
|
0.320 |
GeneticVariation
|
disease |
LHGDN |
SUMO1 polymorphisms are associated with non-syndromic cleft lip with or without cleft palate.
|
18983974 |
2008 |
Cleft Palate
|
0.320 |
Biomarker
|
disease |
BEFREE |
Because SUMO-1 was also involved in cleft lip/palate in human patients, the previous findings provided a powerful rationale to question whether SUMO-1 was mutated in infants born with cleft palates and ASDs.
|
21563299 |
2011 |
Cleft Palate
|
0.320 |
Biomarker
|
disease |
CTD_human |
SUMO1 haploinsufficiency leads to cleft lip and palate.
|
16990542 |
2006 |
OROFACIAL CLEFT 5
|
0.300 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
SUMO1 haploinsufficiency leads to cleft lip and palate.
|
16990542 |
2006 |
Cleft palate, isolated
|
0.300 |
Biomarker
|
disease |
CTD_human |
SUMO1 haploinsufficiency leads to cleft lip and palate.
|
16990542 |
2006 |
Micrognathism
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
Hypoplasia of the maxilla
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
Microdontia (disorder)
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
Unilateral cleft lip
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
Unilateral cleft palate
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
Alzheimer's Disease
|
0.090 |
AlteredExpression
|
disease |
BEFREE |
The opposite effect of Aβ and oxidative/excitotoxic stimuli on SUMO1 modification may cause the pathological stage-associated change in the level of SUMO-modified proteins in the AD mouse brain.
|
29660340 |
2018 |