UCHL1, ubiquitin C-terminal hydrolase L1, 7345

N. diseases: 260; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.330 Biomarker disease BEFREE Upregulation of Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) Mediates the Reversal Effect of Verapamil on Chemo-Resistance to Adriamycin of Hepatocellular Carcinoma. 29627846 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.330 Biomarker disease BEFREE The upregulation of NAE1, UBE2M, and UCHL1 in HCC was associated with aggressive characteristics and poor OS and RFS in patients with HCC after hepatectomy. 29846044 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.330 AlteredExpression disease BEFREE UCHL1 is expressed in all normal tissues and immortalized normal epithelial cell lines, but was low or silenced in 77% (10/13) of HCC cell lines, which is well correlated with its promoter methylation status. 18666234 2008
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.330 AlteredExpression disease LHGDN UCHL1 is expressed in all normal tissues and immortalized normal epithelial cell lines, but was low or silenced in 77% (10/13) of HCC cell lines, which is well correlated with its promoter methylation status. 18666234 2008
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.330 Biomarker disease CTD_human UCHL1 is expressed in all normal tissues and immortalized normal epithelial cell lines, but was low or silenced in 77% (10/13) of HCC cell lines, which is well correlated with its promoter methylation status. 18666234 2008