UCP2, uncoupling protein 2, 7351

N. diseases: 235; N. variants: 5
Disease: Fatty Liver ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.540 AlteredExpression disease BEFREE Oxidative stress and mitochondrial uncoupling protein 2 expression in hepatic steatosis induced by exposure to xenobiotic DDE and high fat diet in male Wistar rats. 31022254 2019
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.540 AlteredExpression disease BEFREE Severe liver steatosis with down-regulation of PPAR-α and UCP2 and up-regulation of SREBP-1c, IL-6 and SOD-1 was observed in the female offspring born to deficient dams. 28219837 2017
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.540 AlteredExpression disease BEFREE We conclude that TRPV1 long-time activation might prevent high-fat diet-induced fatty liver in mice through upregulation of hepatic UCP2. 22395410 2012
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.540 Biomarker disease RGD The effect of rat strain, diet composition and feeding period on the development of a nutritional model of non-alcoholic fatty liver disease in rats. 21114362 2011
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.540 Biomarker disease BEFREE UCP2 is a recently identified fatty acid-responsive mitochondrial inner membrane carrier protein showing wide tissue distribution with a substantially increased presence in fatty liver. 15970480 2005
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.540 Biomarker disease CTD_human Mitochondrial adaptations to obesity-related oxidant stress. 10860543 2000