UCP3, uncoupling protein 3, 7352

N. diseases: 66; N. variants: 18
Disease: Congestive heart failure ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.220 Biomarker disease BEFREE The uncoupling protein 3 (UCP3) plays a cardio-protective role in early heart failure development. 29694982 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.220 Biomarker disease RGD Doxorubicin-induced heart failure was associated with significant decreases in UCP2 and UCP3 protein expression compared with nonfailing hearts (P < 0.05). 20809120 2011
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.220 Biomarker disease BEFREE Although LVAD treatment improved clinical markers of heart failure (decrease of left ventricular diastolic dimension and normalization of serum sodium), only UCP3 expression reversed to non-failing transcript levels following mechanical unloading. 12145475 2002