Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
In vivo, VEGF controls the correct migration of facial branchiomotor neurons in the developing hindbrain and stimulates the proliferation of neural stem cells in enriched environments and after cerebral ischemia.
|
16784838 |
2007 |
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, the authors assessed the effect of combined gene therapy with VEGF<sub>165</sub> and SDF-1 in a rat model of cerebral infarction.
|
27982773 |
2017 |
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Transplantation of VEGF-mediated bone marrow mesenchymal stem cells promotes functional improvement in a rat acute cerebral infarction model.
|
28823954 |
2017 |
Cerebral Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The aim of this study was to investigate whether miR-490 was involved in the regulation of angiogenesis after cerebral infarction by regulating vascular endothelial growth factor (VEGF) expression.
|
30536336 |
2018 |
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
The expressions of vascular endothelial growth factor (VEGF) and matrix metalloproteinase 9 (MMP-9) were supposed to show the changing circumstances for neural generation under cerebral ischemia.
|
31418133 |
2019 |
Cerebral Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia.
|
16641198 |
2006 |
Cerebral Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
While Sesn2, Nrf2, HO-1, and VEGF were significantly increased following cerebral ischemia, overexpression of Sesn2 further increased their expression.
|
31085280 |
2019 |
Cerebral Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The possible mechanism is that PMVs facilitate angiogenesis after cerebral infarction through promoting the expressions of VEGF, Ang-1 and N-Cadherin.
|
31005253 |
2019 |
Cerebral Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
EPO promotes VEGE and its receptor (KDR) expression and participates in the regulation of HIF-1α and eNOS protein expression through the activation of AMPK-KLF2 signaling pathways to promote new vascular development after cerebral ischemia.
|
31679265 |
2019 |
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Overexpressed lncRNA ANRIL upregulates VEGF and promotes angiogenesis by activating NF-κB signaling pathway in DM + CI rats..
|
28060742 |
2017 |
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Effects of ischemic post-conditioning on neuronal VEGF regulation and microglial polarization in a rat model of focal cerebral ischemia.
|
29570780 |
2018 |
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Encapsulated vascular endothelial growth factor-secreting cell grafts have neuroprotective and angiogenic effects on focal cerebral ischemia.
|
16121981 |
2005 |
Cerebral Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Our results point out that BAI2 controls VEGF transcription through GABP under normal conditions and cerebral ischemia.
|
16412436 |
2006 |
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Several reports recently suggested that vascular endothelial growth factor (VEGF) may have a therapeutic benefit against experimental cerebral infarction animal models.
|
17881973 |
2007 |
Cerebral Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Transplantation of BMSCs stably expressing mutant HIF1α significantly improved motor function, reduced cerebral infarction and increased VEGF protein expression revascularization at days 7, 14 and 28 (p<0.05).
|
25270619 |
2014 |
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
This study tested the hypothesis that neuropilin-1 (NP-1), an alternative VEGF receptor, regulates the response to cerebral ischemia by modulating PARP expression and, in turn, apoptosis inhibition by VEGF.
|
23816753 |
2013 |
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
A previous in vivo study demonstrated that intracerebroventricular injection of basic fibroblast growth factor (bFGF) in middle cerebral artery occlusion rats increased the expression of caveolin-1 (cav-1) and vascular endothelial growth factor (VEGF) in cerebral ischemia penumbra.
|
29299743 |
2018 |
Cerebral Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Here, OGD-PBMCs were identified to secrete remodelling factors, including the vascular endothelial growth factor and transforming growth factor-β in vitro, while intra-arterial administration of OGD-PBMCs at 7 days after focal cerebral ischemia prompted expression of such factors in the brain parenchyma at 28 days following focal cerebral ischemia in vivo.
|
31728010 |
2019 |
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our data demonstrated that hypoxic preconditioning increased BBB disruption through a VEGF related pathway and suggest the possibility of aggravation of brain edema by hypoxic preconditioning in the early stages of cerebral ischemia.
|
27823555 |
2017 |
Cerebral Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
These results demonstrated that liraglutide promoted angiogenesis and long-term recovery of cerebral ischemia through increasing the expression of VEGF.
|
29395648 |
2018 |
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
This review discusses the feasibility of gene therapy using an HVJ-based non-viral vector containing the VEGF or HGF gene for cerebral ischemia.
|
16146767 |
2006 |
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Intraventricular pre-treatment with rAAV-VEGF induces intracranial hypertension and aggravates ischemic injury at the early stage of transient focal cerebral ischemia in rats.
|
18534058 |
2008 |
Cerebral Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Enzyme-linked immunosorbent assay (ELISA) was performed to determine the level of vascular endothelial growth factor (VEGF) in the serum of CI patients.
|
31173308 |
2019 |
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
And explore the mechanism of VEGF to promote angiogenesis of functional recovery in focal cerebral ischemia of rat.
|
30041898 |
2018 |
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Vascular endothelial growth factor aggravates cerebral ischemia and reperfusion-induced blood-brain-barrier disruption through regulating LOC102640519/HOXC13/ZO-1 signaling.
|
29842876 |
2018 |