|
Asthma
|
0.400 |
Biomarker
|
disease |
BEFREE |
These findings provide evidence that VEGF may play an important role in angiogenesis and subsequent airway remodeling in bronchial asthma.
|
11398081 |
2001 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
CTD_human |
One of the histological hallmarks of inflammation is angiogenesis, but the possible role of vascular endothelial growth factor (VEGF), a potent angiogenic cytokine, in TDI-induced asthma is unknown.
|
11907124 |
2002 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
BEFREE |
We conclude that ASM-derived VEGF, through modulation of the extracellular matrix, may play an important role in airway remodeling seen in asthma.
|
14633511 |
2004 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
LHGDN |
Vascular endothelial growth factor-induced secretion of fibronectin is ERK dependent.
|
14633511 |
2004 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
CTD_human |
Acute and chronic changes of vascular endothelial growth factor (VEGF) in induced sputum of toluene diisocyanate (TDI)-induced asthma patients.
|
15201500 |
2004 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
LHGDN |
Acute and chronic changes of vascular endothelial growth factor (VEGF) in induced sputum of toluene diisocyanate (TDI)-induced asthma patients.
|
15201500 |
2004 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
LHGDN |
Vascular endothelial growth factor-mediated induction of angiogenesis by human rhinoviruses.
|
16461129 |
2006 |
|
Asthma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
VEGF levels were measured in respiratory secretions from patients with asthma, before and during rhinovirus-induced exacerbations.
|
16461129 |
2006 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Nasal VEGF was also measured in a cohort of asthmatics with verified rhinovirus and respiratory syncytial virus (RSV) infection.
|
16555282 |
2006 |
|
Asthma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We sought to evaluate the effects of variations in the gene coding VEGF receptor (VEGFR) 2 on intermediate phenotypes of asthma in the Korean population.
|
16630933 |
2006 |
|
Asthma
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
Administration of VEGF receptor inhibitors reduced the pathophysiologic signs of asthma and decreased the increased expression of MMP-9 after ovalbumin inhalation.
|
16645174 |
2006 |
|
Asthma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Relationship between neurokinin 2 receptor gene polymorphisms and serum vascular endothelial growth factor levels in patients with toluene diisocyanate-induced asthma.
|
16961715 |
2006 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
LHGDN |
Immunomodulatory role of vascular endothelial growth factor and angiopoietin-1 in airway remodeling.
|
17168735 |
2006 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Experimental models and expression studies suggest that anti-vascular endothelial growth factor (VEGF) receptor strategies may be of use in patients with emphysema, whereas anti-HER1-directed strategies may be more useful in patients with pulmonary mucus hypersecretion, as seen in chronic bronchitis and asthma.
|
17406066 |
2007 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
LHGDN |
The aim of this study was to compare vascular endothelial growth factor (VEGF) and its receptor foetal liver kinase (Flk)-1 expression between seasonal AR patients with or without asthma and non-allergic controls as well as that between AR patients with and without asthma.
|
17651148 |
2007 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
BEFREE |
The cytokine and potent angiogenic factor vascular endothelial growth factor (VEGF) plays an important role in airway remodelling in various airway diseases such as idiopathic pulmonary fibrosis, pulmonary hypertension, lung cancer, asthma and chronic obstructive pulmonary disease (COPD).
|
17906365 |
2007 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Insights into the importance of vascular endothelial growth factor and angiogenesis in asthma pathogenesis now lead to potential new therapeutic possibilities and elucidate why recent advances in asthma therapeutics have been so successful.
|
18188016 |
2008 |
|
Asthma
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
Vascular endothelial growth factor overexpression in induced sputum of children with bronchial asthma.
|
18298425 |
2009 |
|
Asthma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The objective of the present study was to determine whether VEGF single nucleotide polymorphisms (SNPs) are associated with asthma, lung function and airway responsiveness.
|
19196819 |
2009 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
CTD_human |
Manganese (II) induces chemical hypoxia by inhibiting HIF-prolyl hydroxylase: implication in manganese-induced pulmonary inflammation.
|
19263519 |
2009 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
BEFREE |
C. pneumoniae infection of BECs may play a role in the pathogenesis of asthma through the enhanced production of CCL20 and VEGF.
|
19479364 |
2009 |
|
Asthma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The levels of HIF-1α and VEGF increased in lung tissue and bronchial fluid of patients with asthma and in the nasal fluid of patients with rhinitis after challenge.
|
21517900 |
2011 |
|
Asthma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Allergen treatment and lung-specific vascular endothelial growth factor (VEGF) expression induced asthma-like pathologies in the murine lungs.
|
21595947 |
2011 |
|
Asthma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
It has been shown that treatment of asthma patients decreases VEGF levels, and inhibition of VEGF diminishes asthma symptoms in mice.
|
22519966 |
2012 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Abnormal histone methylation is responsible for increased vascular endothelial growth factor 165a secretion from airway smooth muscle cells in asthma.
|
22689881 |
2012 |