cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
The aim of this study was to determine whether VEGF/VEGFRs could be used as prognostic biomarkers in patients with CC.
|
31236742 |
2019 |
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Formononetin can inhibit the growth of cervical cancer and reduce the mRNA and protein expression levels of HIF-1α and VEGF in mouse cervical cancer.
|
31452725 |
2019 |
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
We compared the plasma levels of M-CSF and VEGF to the ones of commonly accepted tumor markers CA 125and SCC-Ag in three groups of patients: 1. the cervical cancer group (patients with either squamous cell carcinoma or adenocarcinoma); 2. the cervical dysplasia group; 3. the control group.
|
31035945 |
2019 |
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Moreover, data revealed positive correlation between plasma level and cervical cancer cell expression of VEGF.
|
31704874 |
2019 |
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Our study demonstrated that PSMA7 silencing can suppress CC cell proliferation and VEGF expression in addition to promoting cell apoptosis through inhibiting the UPP signaling pathway.
|
29247526 |
2019 |
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
In the total CC, stage I, and stage II groups, all tested parameters showed statistically significant area under the receiver operating characteristics curve (AUC), but maximum range was obtained for the combination VEGF + SCC-Ag (I: 0.9146, II: 0.8941, III + IV: 0.9139, total CC group: 0.9347).
|
30037277 |
2018 |
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Vascular endothelial growth factor (VEGF) has emerged as a therapeutic target in several malignancies, including cervical cancer.
|
29666026 |
2018 |
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
VEGF expression is significantly positively correlated with miR-21 expression, and the high levels of VEGF and miR-21 predict unfavorable prognosis of cervical cancer.
|
30338794 |
2018 |
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
CD31 and vascular endothelial growth factor (VEGF) were stained to reflect tumor angiogenesis in 67 CC tissues.
|
30458457 |
2018 |
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Deregulation of LIMD1-VHL-HIF-1α-VEGF pathway is associated with different stages of cervical cancer.
|
29654110 |
2018 |
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
A significantly higher expression of VEGF was identified in post-radiotherapy relapsed/persistent cervical cancer compared with typical specimens from cervical cancer.
|
29928441 |
2018 |
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
The results of the present study suggested that TSLP derived of cervical cancer cells may indirectly stimulate angiogenesis of HUVECs, by upregulating IL-8 and VEGF production, in a co-culture model between cervical cancer cells and EOS, therefore promoting the development of cervical cancer.
|
29344192 |
2017 |
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Although anti-vascular endothelial growth factor drugs have shown great promise as a therapeutic target for treatment of advanced cervical cancer, drug resistance and class-specific side effects negate long-term benefits.
|
28720059 |
2017 |
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Prognostic role of vascular endothelial growth factor in cervical cancer: a meta-analysis.
|
28177889 |
2017 |
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
The present study investigated the clinicopathological significance of the coexpression of LAPTM4B-35 and VEGF in patients with cervical cancer.
|
26526574 |
2016 |
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Data have shown that VEGF expression levels are associated with hTERT expressions and telomerase activity in HPV-positive cervical cancer tissues and cells.
|
26067630 |
2015 |
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
To investigate the effect of recombinant human p53 adenovirus injection combined with paclitaxel on human cervical cancer HeLa cell proliferation, apoptosis and expression of vascular endothelial growth factor (VEGF).
|
25855930 |
2015 |
cervical cancer
|
0.400 |
Biomarker
|
disease |
CTD_human |
PIAS3, SHP2 and SOCS3 Expression patterns in Cervical Cancers: Relevance with activation and resveratrol-caused inactivation of STAT3 signaling.
|
26432044 |
2015 |
cervical cancer
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Specific VEGF variants (rs699947, rs1570360) and haplotype (CTGCCAG) may contribute to the development of CC among Tunisian women.
|
25541433 |
2015 |
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Effects of VEGF suppression by small hairpin RNA interference combined with radiotherapy on the growth of cervical cancer.
|
25061734 |
2014 |
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The mRNA expression level of TLR8 in the patients with cervical cancer and Hela cells were up-regulated, it consistent with the increased expression of VEGF and Bcl-2.
|
24782650 |
2014 |
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Function of inducible nitric oxide synthase in the regulation of cervical cancer cell proliferation and the expression of vascular endothelial growth factor.
|
24297386 |
2014 |
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
To figure out the involved signaling pathways, we applied specific inhibitors for ERK/MAPK, JNK, and PI3K/Akt signaling pathways, respectively, to VEGFa-overexpressing cervical cancer lines and found that only inhibition of PI3K/Akt signal transduction abolished VEGFa-induced increases in cell growth and invasiveness.
|
25135429 |
2014 |
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Our findings have demonstrated that the miR-196b/HOXB7/VEGF pathway plays an important role in cervical cancer progression; hence targeting this pathway could be a promising therapeutic strategy for the future management of this disease.
|
23861821 |
2013 |
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
To detect vascular endothelial growth factor (VEGF)-C mRNA expression in surgically resected tissues of 'pathologic N0' (pN0) cervical cancer; to investigate the relevance of VEGF-C mRNA expression to clinicopathological factors, lymph node recurrence and prognosis in early stage cervical cancer.
|
23963849 |
2013 |