VIM, vimentin, 7431

N. diseases: 644; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group CTD_human Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K. 25330770 2014
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group CTD_human MCF-7 cells expressing nuclear associated lysyl oxidase-like 2 (LOXL2) exhibit an epithelial-to-mesenchymal transition (EMT) phenotype and are highly invasive in vitro. 24014025 2013
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 PosttranslationalModification group BEFREE We therefore quantified Vimentin DNA methylation using MALDI-TOF mass spectrometry in breast tumors and matched normal pairs in association with gene expression and survival in a hospital-based study of breast cancer patients. 23239149 2013
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group BEFREE Here, we show that human breast tumor biomarker miR-30c regulates invasion by targeting the cytoskeleton network genes encoding twinfilin 1 (TWF1) and vimentin (VIM). 23224145 2013
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group BEFREE Treatments of human non-tumorigenic mammary epithelial and breast tumor cells with Lidocaine or Tetracaine caused rapid collapse of vimentin filaments. 21069453 2011
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group CTD_human Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization. 21501481 2011
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group BEFREE Since vimentin and laminin staining is widely used by pathologists for diagnostic purposes, thus demonstrating the robustness of their specific antibodies, the immunohistochemical evaluation of these two molecules could be used in identification of basal-like breast tumours in both sporadic/familial cases. 17105822 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 AlteredExpression group LHGDN Down-regulation of vimentin expression inhibits carcinoma cell migration and adhesion. 17585878 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group BEFREE Our results therefore implicate SIP1 in the regulation of vimentin observed in the EMT associated with breast tumor cell migration, a pathway that may contribute to the metastatic progression of breast cancer. 16568083 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group LHGDN Our results therefore implicate SIP1 in the regulation of vimentin observed in the EMT associated with breast tumor cell migration, a pathway that may contribute to the metastatic progression of breast cancer. 16568083 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group BEFREE This is mainly supported by the significantly higher incidence of vimentin-expressing breast cancers compared to any other myoepithelial breast tumours and the fact that vimentin is already observed in ductal in situ components. 15906273 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group LHGDN Transactivation of vimentin by beta-catenin in human breast cancer cells. 12750294 2003