|
Hypertensive disease
|
0.590 |
Biomarker
|
group |
BEFREE |
VWF antigen (VWF:Ag) was higher in type 1 VWD patients with hypertension [difference: 0·23 iu/ml, 95% confidence interval (CI): 0·11-0·35], diabetes mellitus (0·11 iu/ml, 95% CI: -0·02 to 0·23), cancer (0·14 iu/ml, 95% CI: 0·03-0·25) and thyroid dysfunction (0·14 iu/ml, 95% CI: 0·03-0·26) than in patients without these comorbidities (all corrected for age, sex and blood group).
|
29767844 |
2018 |
|
Hypertensive disease
|
0.590 |
Biomarker
|
group |
BEFREE |
To better understand the early phases of vascular deterioration in a young, healthy population, we investigated, cross-sectionally, whether biomarkers of endothelial function (intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and von Willebrand factor antigen (vWF<sub>ag</sub>)) are associated with IGF-1 in a healthy study population forming part of the larger African Prospective study on the Early Detection and Identification of Cardiovascular diseases and Hypertension (African-PREDICT).
|
29936324 |
2018 |
|
Hypertensive disease
|
0.590 |
Biomarker
|
group |
BEFREE |
Whether low VWF protects against HTN is unknown.
|
27655998 |
2018 |
|
Hypertensive disease
|
0.590 |
Biomarker
|
group |
BEFREE |
The aim of this study was to evaluate the relationship between vWf maternal plasma concentration and maternal and fetal Doppler flow measurements in pregnancies complicated by hypertension.
|
29621786 |
2018 |
|
Hypertensive disease
|
0.590 |
Biomarker
|
group |
CTD_human |
Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole.
|
22352330 |
2012 |
|
Hypertensive disease
|
0.590 |
AlteredExpression
|
group |
BEFREE |
VWF and FVIII levels returned to baseline by day 14. rhIL-11 was well tolerated with less than grade-1 hypertension, hypokalaemia and fluid retention.
|
18680527 |
2008 |
|
Hypertensive disease
|
0.590 |
GeneticVariation
|
group |
BEFREE |
Five polymorphisms in five genes, CAST(calpastatin), LIPC (hepatic lipase), SLC4A1 (band 3 anion transporter), TRH (thyrotropin-releasing hormone), and VWF (von Willebrand factor), were significantly associated with both blood pressure variation and hypertension.
|
17137217 |
2006 |
|
Hypertensive disease
|
0.590 |
Therapeutic
|
group |
RGD |
Impact of alpha-tocopherol and vitamin C on endothelial markers in rats with streptozotocin-induced diabetes.
|
14737039 |
2004 |
|
Hypertensive disease
|
0.590 |
Biomarker
|
group |
CTD_human |
The levels of adhesion molecules (intercellular cell adhesion molecule-1 [ICAM-1], E-selectin, P-selectin), von Willebrand factor (vWf) and endothelin-1 were measured in patients with hypertension without any other risk factors of atherosclerosis before and after treatment with quinapril (n = 22) and in normotensive controls (n = 22).
|
12149661 |
2002 |
|
Hypertensive disease
|
0.590 |
Biomarker
|
group |
CTD_human |
The objective of the investigation was to assess whether circulating adhesion molecules, von Willebrand factor (vWf) and endothelin-1 are elevated in patients with mild uncomplicated essential hypertension without further risk factors of atherosclerosis and whether they could serve as indicators of endothelial dysfunction in this form of hypertension.
|
12425201 |
2002 |
|
Hypertensive disease
|
0.590 |
Biomarker
|
group |
BEFREE |
We identified the ACE I/D genotype and measured the plasma levels of markers of endothelial cell damage (von Willebrand factor [vWF] and thrombomodulin) and of coagulation activation (prothrombin fragment F1 + 2 [F1 + 2]) in 318 asymptomatic elderly patients with hypertension, aged 59-93 years.
|
9708474 |
1998 |
|
Hypertensive disease
|
0.590 |
Biomarker
|
group |
BEFREE |
We compared sodium-lithium countertransport activity (SLC Vmax), plasma lipoprotein(a) and von Willebrand factor (vWf) concentrations, incidence of vascular disease, and incidence of hypertension in 37 first degree relatives of 23 patients with stable IgAN and 33 first degree relatives of 17 patients with progressive IgAN.
|
9306351 |
1997 |
|
Hypertensive disease
|
0.590 |
AlteredExpression
|
group |
BEFREE |
Genotype frequencies were in Hardy-Weinberg equilibrium and genotype did not relate to vWF levels: means (95% CI) were AA 1.29 (1.29-1.44) IU ml-1 n = 3; AG 1.28 (1.22-1.26) IU ml-1 n = 48; GG 1.29 (1.25-1.39) IU ml-1 n = 155. vWF correlated with age (r = 0.23 p < 0.0005), duration of diabetes (r = 0.23, p < 0.001), and fibrinogen (r = 0.22, p = 0.002) in the patient group, but was unrelated to blood lipids, HbA1C, body mass index, glucose, hypertension, and smoking.
|
8862946 |
1996 |