Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
Endothelial surface and circulating glycoprotein von Willebrand factor (vWF) regulates platelet adhesion and is associated with thrombotic diseases, including ischemic stroke, myocardial infarction, and peripheral vascular disease.
|
30987839 |
2019 |
Myocardial Infarction
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction.
|
30366922 |
2019 |
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
Furthermore, compared with the MI group, the plasma levels of TXA2, ET-1 and vWF contents signififi cantly decreased in the MI+SSYX group, and the ET-1 mRNA expression levels of myocardium in the border zone significantly decreased, and the VEGF, PGI2 and eNOS mRNA expression levels signififi cantly increased (all P<0.05).
|
30656600 |
2019 |
Myocardial Infarction
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
A reduced plasma ADAMTS13 activity and increased VWF levels are associated with a higher risk of myocardial infarction.
|
30471507 |
2019 |
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
ApoA-I, HDL-C, and inflammatory markers (C-reactive protein [CRP], serum amyloid A (SAA), fibrinogen, von Willebrand factor [vWF], and D-dimer) were measured from blood samples of 1028 patients drawn 2 months after an index myocardial infarction (MI).
|
28391888 |
2017 |
Myocardial Infarction
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
During the 2-month interval prior to an event, cases (n = 48) had higher levels of the vWF and ADAMTS13 than controls (n = 95; P = .05), but significance was lost after adjusting for the baseline differences in myocardial infarction, unstable angina, and stroke.
|
27317583 |
2017 |
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
Moreover, experimental mouse models of ischemic stroke and myocardial infarction have further supported VWF as a potential therapeutic target.
|
26771163 |
2016 |
Myocardial Infarction
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
It is well established that high plasma von Willebrand factor (VWF) levels are associated with an increased risk of arterial thrombosis, including myocardial infarction and ischemic stroke.
|
21342431 |
2011 |
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
RGD |
Effects of Radix et Rhizoma Rhodiolae Kirilowii on expressions of von Willebrand factor, hypoxia-inducible factor 1 and vascular endothelial growth factor in myocardium of rats with acute myocardial infarction.
|
19435557 |
2009 |
Myocardial Infarction
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
High plasma levels of beta2-glycoprotein I remained protective for myocardial infarction despite high levels of VWF.
|
19706887 |
2009 |
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
LHGDN |
Evidence that high von Willebrand factor and low ADAMTS-13 levels independently increase the risk of a non-fatal heart attack.
|
18194418 |
2008 |
Myocardial Infarction
|
0.300 |
GeneticVariation
|
disease |
LHGDN |
The G/A polymorphism of the von Willebrand factor gene failed to show any association with MI or coronary atherosclerosis in this series of men.
|
17619827 |
2008 |
Myocardial Infarction
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
The G/A polymorphism of the von Willebrand factor gene failed to show any association with MI or coronary atherosclerosis in this series of men.
|
17619827 |
2008 |
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
LHGDN |
ADAMTS13 and von Willebrand factor and the risk of myocardial infarction in men.
|
17053057 |
2007 |
Myocardial Infarction
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
We examined the effect of G894T polymorphism on endothelial function, on markers of endothelial cells injury and activation such as von Willebrand factor (vWF) and on serum levels of proinflammatory cytokines such as interleukins 6 (IL-6) and 1b (IL-1b), in young myocardial infarction (MI) survivors.
|
16337503 |
2006 |
Myocardial Infarction
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
The thrombospondin-1 N700S polymorphism is associated with early myocardial infarction without altering von Willebrand factor multimer size.
|
16684956 |
2006 |
Myocardial Infarction
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
G894T polymorphism on the eNOS gene increases the risk for premature MI and modifies the response of vascular endothelium during the acute phase of MI by affecting the release of vWF, IL-6, and oxidative stress status, an effect diminished one year after the event.
|
16168297 |
2005 |
Myocardial Infarction
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
We conducted this genetic study to test whether the ABO O1 allele is associated with low vWF plasma levels and with a reduced risk of MI.
|
15166945 |
2004 |
Myocardial Infarction
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
We assessed the contribution of classical cardiovascular risk factors (dyslipidaemia, hypertension, and prior myocardial infarction), and of new cardiovascular risk factors (microalbuminuria, von Willebrand factor, sVCAM-1 and C-reactive protein) to the mortality risk during nearly 10 years of follow up.
|
12534452 |
2002 |
Myocardial Infarction
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
The -1185 A/G and -1051 G/A dimorphisms in the von Willebrand factor gene promoter and risk of myocardial infarction.
|
11736957 |
2001 |