WNT2, Wnt family member 2, 7472

N. diseases: 96; N. variants: 9
Disease: Neoplasm Metastasis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.060 AlteredExpression phenotype BEFREE In human colorectal cancer (CRC), WNT2 is selectively elevated in cancer-associated fibroblasts (CAFs), leading to increased invasion and metastasis. 31667643 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.060 AlteredExpression phenotype BEFREE The results indicated that Wnt2 is overexpressed in gastric cancer and is implicated in metastasis and TNM stage. 30127872 2018
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.060 Biomarker phenotype BEFREE In line, WNT2 also promotes tumor growth, invasion and metastasis in vivo. 28553956 2017
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.060 AlteredExpression phenotype BEFREE WNT2 overexpression in cervical cancer was associated with β-catenin activation and induction of EMT, which further contributed to metastasis in cervical cancer. 27513465 2016
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.060 Biomarker phenotype BEFREE Pleiotrophin (PTN) is a secreted growth factor with angiogenic activity that has been found to contribute to the growth and metastasis of tumors including melanoma. 15496960 2005
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.060 Biomarker phenotype BEFREE Herein we use ribozyme targeting of pleiotrophin (PTN) in metastatic human melanoma cells to assess the significance of this secreted growth factor for angiogenesis and metastasis. 8962127 1996