WNT10B, Wnt family member 10B, 7480

N. diseases: 90; N. variants: 23
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.350 Biomarker disease BEFREE Wnt10B was previously shown to be involved in breast cancer development. 28599424 2017
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.350 Biomarker disease BEFREE Moreover, exosomes have a key role in paracrine Wnt10b transport from fibroblasts to breast cancer epithelial cells. 28394344 2017
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.350 Biomarker disease BEFREE Furthermore, our studies supports an autocrine activation primed by the formation of WNT10B-FZD4/5 complexes in the breast cancer MCF7 cells that express the WNT10B<sup>IVS1</sup>. 27853307 2016
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.350 Biomarker disease CTD_human Effects of pyrethroid insecticides and estrogen on WNT10B proto-oncogene expression. 12437293 2002
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.350 AlteredExpression disease BEFREE WNT10B mRNA was relatively highly expressed in TE3, TE6, TE10, TE11 (esophageal cancer), Hs700T (pancreatic cancer), SKG-IIIa, HeLa S3 (cervical cancer), and T-47D (breast cancer). 12239602 2002
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.350 AlteredExpression disease BEFREE In contrast, using both methods, WNT10B expression was found to be elevated in 3 of 50 primary breast carcinomas. 9121776 1997