WT1, WT1 transcription factor, 7490

N. diseases: 446; N. variants: 61
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
0.350 AlteredExpression disease BEFREE Wilms' tumor 1 (WT1) is expressed in most glioblastoma samples, and immunotherapy targeting WT1 has proven to be effective in recurrent glioblastoma. 24403445 2014
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
0.350 Biomarker disease CTD_human Wilms' tumor 1 silencing decreases the viability and chemoresistance of glioblastoma cells in vitro: a potential role for IGF-1R de-repression. 20820871 2011
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
0.350 Biomarker disease BEFREE Wilms' tumor 1 silencing decreases the viability and chemoresistance of glioblastoma cells in vitro: a potential role for IGF-1R de-repression. 20820871 2011
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
0.350 Biomarker disease BEFREE Effect of WT1 gene silencing on the tumorigenicity of human glioblastoma multiforme cells. 19392599 2010
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
0.350 AlteredExpression disease BEFREE Down-regulation of Wilms' tumor 1 expression in glioblastoma cells increases radiosensitivity independently of p53. 17206472 2007
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
0.350 Biomarker disease LHGDN Our results suggest that the WT1 gene may play an important role in the tumorigenesis of glioblastoma, in contrast to medulloblastoma, and be integral in the development of the immunotherapy targeting WT1 protein in patients with glioblastoma. 15696971 2004