XBP1, X-box binding protein 1, 7494

N. diseases: 234; N. variants: 6
Disease: Fatty Liver ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.330 Biomarker disease BEFREE Reactivation of XBP1s in mice lacking hepatic IRE1α restores COPII-mediated lipoprotein secretion and reverses the fatty liver and hypolipidemia phenotypes. 31123148 2019
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.330 Biomarker disease BEFREE Collectively, we present direct evidence supporting the importance of XBP1 acetylation in ER stress-induced hepatic steatosis. 31541078 2019
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.330 Biomarker disease BEFREE Fibroblast growth factor 21 is regulated by the IRE1α-XBP1 branch of the unfolded protein response and counteracts endoplasmic reticulum stress-induced hepatic steatosis. 25170079 2014
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.330 Biomarker disease CTD_human The adaptive endoplasmic reticulum stress response to lipotoxicity in progressive human nonalcoholic fatty liver disease. 24097666 2014