XBP1, X-box binding protein 1, 7494

N. diseases: 234; N. variants: 6
Disease: Insulin Resistance ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021655
Disease: Insulin Resistance
Insulin Resistance 		0.300 Therapeutic phenotype CTD_human Our results reveal that XBP1s reduces hepatic lipogenic gene expression and improves hepatosteatosis in mouse models of obesity and insulin resistance, which leads us to conclude that XBP1s has anti-lipogenic properties in the liver. 27325692 2016