XRCC1, X-ray repair cross complementing 1, 7515

N. diseases: 410; N. variants: 39
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001430
Disease: Adenoma
Adenoma
0.030 GeneticVariation group BEFREE The XRCC1 399Gln allele was associated with a reduction of risk of high-risk adenomas (OR 0.62, 95% CI 0.41-0.96). 16542436 2006
CUI: C0001430
Disease: Adenoma
Adenoma
0.030 GeneticVariation group BEFREE We have previously reported an inverse association between the XRCC1 codon 399 SNP and adenoma risk among these subjects. 17164360 2006
CUI: C0001430
Disease: Adenoma
Adenoma
0.030 GeneticVariation group BEFREE High omega-6/omega-3 polyunsaturated fatty acid ratios were associated with adenoma risk among subjects with the XRCC1 codon 194 Arg/Arg and codon 399 Gln/Gln or the codon 194 Arg/Trp or Trp/Trp and codon 399 Arg/Arg or Arg/Gln combined genotypes (P for interaction = 0.026). 15767338 2005