Malignant Head and Neck Neoplasm
|
0.100 |
Biomarker
|
disease |
BEFREE |
Evaluation of XRCC1 Gene Polymorphism as a Biomarker in Head and Neck Cancer Patients Undergoing Chemoradiation Therapy.
|
29893275 |
2018 |
Malignant Head and Neck Neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
These data suggest that the XRCC1 Arg399Gln polymorphism is associated with an increased risk of developing HNC, because it correlates with occupational exposure in Tunisian population.
|
24020925 |
2014 |
Malignant Head and Neck Neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Our meta-analysis suggested that the XRCC1 Arg399Gln polymorphism was not a risk factor for HNC susceptibility.
|
24694255 |
2014 |
Malignant Head and Neck Neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
This meta-analysis suggests that the XRCC1 Arg194Trp polymorphism is a risk factor for head and neck cancer in Asian populations.
|
25062722 |
2014 |
Malignant Head and Neck Neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The XRCC1 Arg194Trp polymorphism was significantly associated with HNC risk in studies that were adjusted for smoking and alcohol under the homozygous and heterozygote models.
|
24497981 |
2014 |
Malignant Head and Neck Neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Overall, no evidence of significant association was observed between XRCC1 Arg194Trp, XRCC1 Arg280His, XRCC1 Arg399Gln genotypes and the risk of HNC in any genetic models.
|
24086310 |
2013 |
Malignant Head and Neck Neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
PCR-single-strand conformation polymorphism and DNA sequencing were used to analyze the whole exonic region of XRCC1 in head and neck cancer patients.
|
23055018 |
2013 |
Malignant Head and Neck Neoplasm
|
0.100 |
Biomarker
|
disease |
BEFREE |
Associated risk of XRCC1 and XPD cross talk and life style factors in progression of head and neck cancer in north Indian population.
|
21945240 |
2012 |
Malignant Head and Neck Neoplasm
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, we have found that the deregulation of BER genes (XRCC1 and OGG1) in relation to excessive proliferation (as measured by proliferation marker Ki-67) may be considered as important factors in the development of head and neck cancer in Pakistani population.
|
22798271 |
2012 |
Malignant Head and Neck Neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association between single nucleotide polymorphisms in the XRCC1 and RAD51 genes and clinical radiosensitivity in head and neck cancer.
|
21704413 |
2011 |
Malignant Head and Neck Neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Marginally statistically significant association was found for XRCC1 codon 399 (for Caucasians only), XPD Asp312Asn and XRCC1 codon 194 variants and head and neck cancer.
|
20429839 |
2010 |
Malignant Head and Neck Neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Because of the important role of the XRCC1 gene in DNA repair, we wanted to test the effects of the Arg194Trp and Arg399Gln polymorphisms of XRCC1 on the clinical outcome of head and neck cancer.
|
19846968 |
2009 |
Malignant Head and Neck Neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Polymorphisms of XRCC1, FGFR, and CCND1 have been consistently associated with HNC survival in at least two studies, whereas most of the other polymorphisms have either conflicting data or were from single studies.
|
18349267 |
2008 |
Malignant Head and Neck Neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Polymorphisms of the XRCC1 DNA repair gene in head and neck cancer.
|
15800678 |
2005 |
Malignant Head and Neck Neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Pooling data and DNA specimens from three case-control studies in western Washington State, North Carolina, and Puerto Rico, totaling 555 cases (430 whites) and 792 controls (695 whites), we studied the risk of head and neck cancer in relation to common nonsynonymous single-nucleotide polymorphisms in four DNA repair genes: MGMT (Leu84Phe and Ile143Val), XRCC1 (Arg399Gln), XPD (Lys751Gln), and XRCC3 (Thr241Met).
|
16030112 |
2005 |
Malignant Head and Neck Neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association of DNA repair gene XRCC1 polymorphisms with head and neck cancer in Korean population.
|
15252855 |
2004 |
Malignant Head and Neck Neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
XRCC1 polymorphisms and head and neck cancer.
|
11867203 |
2002 |