Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE While, single nucleotide polymorphisms (SNP) of ERCC1 and XRCC1 have be proved to influence clinical outcome of colorectal cancer patients treated with oxaliplatin-based chemotherapy. 29153096 2017
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE Gene polymorphism in DNA repair genes XRCC1 and XRCC6 and association with colorectal cancer in Swedish patients. 27328741 2016
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE Related databases of Medline, CNKI, and Wanfang were systematic searched for the studies related to XRCC1 rs1799782 C>T polymorphisms and colorectal cancer risk in Chinese Han population. 28230032 2016
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Lack of Association between an XRCC1 Gene Polymorphism and Colorectal Cancer Survival in Thailand. 27221895 2016
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE Association of XRCC1 Arg399Gln Polymorphism with Colorectal Cancer Risk: A HuGE Meta Analysis of 35 Studies. 25921133 2015
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE XRCC1 and ERCC1 polymorphisms are related to susceptibility and survival of colorectal cancer in the Chinese population. 25690281 2015
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE XRCC1 R399Q polymorphism and colorectal cancer risk in the Chinese Han population: a meta-analysis. 25582318 2015
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE Genetic polymorphisms in XRCC1 genes and colorectal cancer susceptibility. 26271249 2015
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE Our results suggest an increased risk for CRC in individuals with XRCC1 Arg194Trp polymorphism suggesting BER repair pathway modulates the risk of developing colorectal cancer in the Kashmiri population. 26434847 2015
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE X-ray repair cross-complementing 1 polymorphism and prognosis of platinum-based chemotherapy in gastric and colorectal cancer: a meta-analysis. 24224851 2014
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE When combined effects of XRCC1 polymorphisms and alcohol consumption were analyzed, we found that the 194Trp or 399Gln alleles further increased the colorectal cancer risk due to high alcohol intake. 24377576 2014
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE This study aimed to investigate the interaction between the presence of a polymorphism of the XRCC1 gene and known risk factors for colorectal cancer in Thailand. 25227862 2014
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE Genetic polymorphism of XRCC1 correlated with response to oxaliplatin-based chemotherapy in advanced colorectal cancer. 23327191 2013
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE Association between XRCC1 and XRCC3 polymorphisms and colorectal cancer risk: a meta-analysis of 23 case-control studies. 23271134 2013
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE The XRCC1 Arg399Gln gene polymorphism and risk of colorectal cancer: a study in Kashmir. 24377605 2013
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE Our meta-analysis provides an evidence for the association between XRCC1 Arg399Gln polymorphism and colorectal cancer risk in Chinese population, and XRCC1 Arg399Gln variant genotypes contribute to increased risk of colorectal cancer in Chinese. 23712778 2013
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE An association selected polymorphisms of XRCC1, OGG1 and MUTYH gene and the level of efficiency oxidative DNA damage repair with a risk of colorectal cancer. 23618615 2013
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Polymorphisms in genes of APE1, PARP1, and XRCC1: risk and prognosis of colorectal cancer in a northeast Chinese population. 23430444 2013
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE This study is the first to provide evidence of importance of XRCC1 and XRCC3 gene polymorphisms for risk of colorectal cancer in the Chinese population. 22524842 2012
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE XRCC1 genotypes of totally 99 patients(37 stage III, 62 stage IV)with advanced colorectal cancer treated with oxaliplatin-based chemotherapy were detected by TaqMan-MGB probe allelic discrimination method. 22549274 2012
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE Therefore, we examined the associations of XRCC1 Arg399Gln, Arg280His, and Arg194Trp polymorphisms with colorectal cancer and the impact of the association between alcohol consumption and colorectal cancer risk. 22186158 2012
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE MLH1 and XRCC1 polymorphisms in Mexican patients with colorectal cancer. 22843073 2012
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE Association between polymorphisms of XRCC1 Arg399Gln and XPD Lys751Gln genes and prognosis of colorectal cancer in a Chinese population. 23317245 2012
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE No association of XRCC1 polymorphisms Arg194Trp and Arg399Gln with colorectal cancer risk. 21612998 2011
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation disease BEFREE The purpose of this study is to evaluate the role of XRCC1 R399Q, R194W, and XRCC3 T241M genotypes in colorectal cancer susceptibility. 19915856 2010