Schizophrenia
|
0.420 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of paliperidone efficacy.
|
27846195 |
2017 |
Schizophrenia
|
0.420 |
Biomarker
|
disease |
BEFREE |
The finding for CACNG5, taken together with the earlier implication of CACNA1C and CACNA1B, strongly suggests a key role for voltage-dependent calcium channel genes in the susceptibility to bipolar disorder and/or schizophrenia.
|
21057379 |
2011 |
Schizophrenia
|
0.420 |
Biomarker
|
disease |
PSYGENET |
The finding for CACNG5, taken together with the earlier implication of CACNA1C and CACNA1B, strongly suggests a key role for voltage-dependent calcium channel genes in the susceptibility to bipolar disorder and/or schizophrenia.
|
21057379 |
2011 |
Schizophrenia
|
0.420 |
Biomarker
|
disease |
PSYGENET |
The promoters for 640 genes were found to be bound by β-catenin, many of which are known schizophrenia (SZ), autism spectrum disorder (ASD), and BD candidates, including CACNA1B, NRNG, SNAP29, FGFR1, PCDH9, and nine others identified in recently published GWASs and genome-wide searches for copy number variants (CNVs).
|
20615089 |
2010 |
Schizophrenia
|
0.420 |
GeneticVariation
|
disease |
BEFREE |
The promoters for 640 genes were found to be bound by β-catenin, many of which are known schizophrenia (SZ), autism spectrum disorder (ASD), and BD candidates, including CACNA1B, NRNG, SNAP29, FGFR1, PCDH9, and nine others identified in recently published GWASs and genome-wide searches for copy number variants (CNVs).
|
20615089 |
2010 |
Seizures
|
0.400 |
Biomarker
|
phenotype |
GENOMICS_ENGLAND |
Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia.
|
30982612 |
2019 |
Global developmental delay
|
0.400 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia.
|
30982612 |
2019 |
Developmental regression
|
0.400 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia.
|
30982612 |
2019 |
Intellectual Disability
|
0.400 |
Biomarker
|
group |
GENOMICS_ENGLAND |
Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia.
|
30982612 |
2019 |
Seizures
|
0.400 |
Biomarker
|
phenotype |
GENOMICS_ENGLAND |
CACNA1B mutation is linked to unique myoclonus-dystonia syndrome.
|
25296916 |
2015 |
Global developmental delay
|
0.400 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
CACNA1B mutation is linked to unique myoclonus-dystonia syndrome.
|
25296916 |
2015 |
Developmental regression
|
0.400 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
CACNA1B mutation is linked to unique myoclonus-dystonia syndrome.
|
25296916 |
2015 |
Intellectual Disability
|
0.400 |
Biomarker
|
group |
GENOMICS_ENGLAND |
CACNA1B mutation is linked to unique myoclonus-dystonia syndrome.
|
25296916 |
2015 |
Seizures
|
0.400 |
Biomarker
|
phenotype |
HPO |
|
|
|
Global developmental delay
|
0.400 |
Biomarker
|
disease |
HPO |
|
|
|
Developmental regression
|
0.400 |
Biomarker
|
disease |
HPO |
|
|
|
Intellectual Disability
|
0.400 |
Biomarker
|
group |
HPO |
|
|
|
Movement Disorders
|
0.300 |
Biomarker
|
group |
GENOMICS_ENGLAND |
Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia.
|
30982612 |
2019 |
Movement Disorders
|
0.300 |
Biomarker
|
group |
GENOMICS_ENGLAND |
CACNA1B mutation is linked to unique myoclonus-dystonia syndrome.
|
25296916 |
2015 |
Peripheral Nervous System Diseases
|
0.300 |
Therapeutic
|
group |
CTD_human |
Inhibition of transmitter release and attenuation of anti-retroviral-associated and tibial nerve injury-related painful peripheral neuropathy by novel synthetic Ca2+ channel peptides.
|
22891239 |
2012 |
Bipolar Disorder
|
0.300 |
Biomarker
|
disease |
PSYGENET |
The finding for CACNG5, taken together with the earlier implication of CACNA1C and CACNA1B, strongly suggests a key role for voltage-dependent calcium channel genes in the susceptibility to bipolar disorder and/or schizophrenia.
|
21057379 |
2011 |
Hyperalgesia
|
0.200 |
Biomarker
|
phenotype |
RGD |
Differential role of N-type calcium channel splice isoforms in pain.
|
17567797 |
2007 |
Experimental Autoimmune Encephalomyelitis
|
0.200 |
Biomarker
|
disease |
RGD |
Distribution of a calcium channel subunit in dystrophic axons in multiple sclerosis and experimental autoimmune encephalomyelitis.
|
11353727 |
2001 |
Dyskinetic syndrome
|
0.110 |
Biomarker
|
disease |
BEFREE |
Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia.
|
30982612 |
2019 |
Dystonia
|
0.110 |
Biomarker
|
phenotype |
BEFREE |
The novel myoclonus-dystonia genes KCTD17 and CACNA1B also implicate abnormal calcium signaling in dystonia.
|
26991507 |
2016 |