Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.150 AlteredExpression disease BEFREE CACNA1c and CACNA2b expression decreased and miR-328 increased in RA and LA during AF. 31131392 2019
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.150 Biomarker disease BEFREE Electrophysiological study was conducted to demonstrate the effect of KCNQ1OT1 and CACNA1C on the Effective refractory period (ERP), interatrial conduction time (IACT), incidence of AF and AF duration of Ang-II-induced mice heart. 30241939 2018
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.150 GeneticVariation disease BEFREE CACNA1C, RyR2) that were associated with LAD, LVA and AF type. 27857207 2016
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.150 Biomarker disease BEFREE Transfection of miRNA-223 by adenovirus-mediated expression enhanced L-type calcium currents and promoted AF in mice while co-injection of a CACNA1C-specific miR-mimic counteracted the effect. 27488468 2016
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.150 Biomarker disease BEFREE CONCLUSIONS We validated the negative regulation between miR-29a-3p and CACNA1C, and found that miR-29a-3p might a potential therapeutic target in the treatment of AF. 27341015 2016
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.150 Biomarker disease HPO