|
Oncocytic Neoplasm
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
These results suggest that BSND is expressed only in normal salivary glands and oncocytic salivary gland tumors such as Warthin's tumor and oncocytoma in addition to the two known organs and the two known renal tumor types mentioned above.
|
28470573 |
2018 |
|
Oxyphilic Adenoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
These results suggest that BSND is expressed only in normal salivary glands and oncocytic salivary gland tumors such as Warthin's tumor and oncocytoma in addition to the two known organs and the two known renal tumor types mentioned above.
|
28470573 |
2018 |
|
Functional abdominal pain
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
AP-FGID: Abdominal Pain Related Functional Gastrointestinal Disorders; BART: Biofeedback-Assisted Relaxation Training; CIN: Chronic Idiopathic Nausea; COS: Core Outcomes Sets; EPS: Epigastric Pain Syndrome; ESPGHAN: European Society for Pediatric Gastroenterology Hepatology and Nutrition; FAP: Functional Abdominal Pain; FD: Functional Dyspepsia; GERD: Gastroesophageal Reflux Disease; GES: Gastric Electrical Stimulation; H<sub>2</sub>RAs: H2 Receptor Antagonists; IBS: irritable bowel syndrome; NASPGHAN: North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition; PDS: Postprandial Distress Syndrome; PPIs: Proton Pump Inhibitor; PROMs: Patient Reported Outcome Measures; RCTs: Randomized Controlled Trials; SSRIs: selective serotonin reuptake inhibitors; TCAs: tricyclic antidepressants.
|
30360666 |
2018 |
|
Dent disease 1
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
As barttin and ClC-5 are both expressed in the thin and thick ascending limbs of the Henle's loop and the collecting duct, interactions between the two proteins could potentially contribute to the phenotypic variability of DD1.
|
30405442 |
2018 |
|
Refractory Cytopenia of Childhood
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Finally, the expression of BSND mRNA in 30 types of tumors other than chromophobe RCC and salivary gland tumors was examined using data from the TCGA database, but none of these tumors exhibited BSND expression.
|
28470573 |
2018 |
|
Marijuana Use
|
0.010 |
Biomarker
|
disease |
BEFREE |
College students were administered self-report questionnaires (Zuckerman Sensation Seeking Scale [ZSS], Barratt Impulsiveness Scale [BIS-11], behavioral measures related to risk-taking and impulsivity (Balloon Analog Risk Task [BART], Experiential Discounting Task [EDT]), and the substance use module of a clinical interview (past-six-month alcohol and marijuana use).
|
29660594 |
2018 |
|
Bartonella Infections
|
0.010 |
Biomarker
|
group |
BEFREE |
A manufactured kit (RealCycler BART, Progenie Molecular) was commercialised shortly thereafter for the detection of Bartonella infection, including Bartonella henselae.
|
29068281 |
2017 |
|
Carcinoma
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Dissecting the regulation of EBV's BART miRNAs in carcinomas.
|
28259048 |
2017 |
|
Linear atrophy
|
0.010 |
Biomarker
|
disease |
BEFREE |
CLC-K/barttin chloride channels are essential for NaCl re-absorption in Henle's loop and for potassium secretion by the stria vascularis in the inner ear.
|
26013830 |
2015 |
|
Kidney Failure, Chronic
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
However, we report here on three brothers with varying degrees of renal dysfunction from mild to end-stage renal disease associated with renal barttin and ClC-K expression.
|
21269598 |
2011 |
|
Stomach Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
The known etiological role of hsa-miR-18 as an oncomiR suggests that miR-BART-5 may function as viral oncomiR as observed in EBV-positive gastric carcinoma patients.
|
21880309 |
2011 |
|
Chronic kidney disease stage 5
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
However, we report here on three brothers with varying degrees of renal dysfunction from mild to end-stage renal disease associated with renal barttin and ClC-K expression.
|
21269598 |
2011 |
|
Nephrocalcinosis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Three patients developed chronic renal failure: one with KCNJ1 mutations during the second decade of age and two with CLCNKB and BSND mutations and without nephrocalcinosis during the first year of life.
|
19096086 |
2009 |
|
Hypochloremic alkalosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
We confirmed in a large cohort of ante/ neonatal BS that deafness, transient hyperkalaemia and severe hypokalaemic hypochloraemic alkalosis orientate molecular investigations to BSND, KCNJ1 and CLCNKB genes, respectively.
|
19096086 |
2009 |
|
Nonsyndromic Deafness
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We demonstrate that BSND mutations with different functional consequences are the basis for either syndromic or nonsyndromic deafness.
|
19646679 |
2009 |
|
Autosomal dominant hypocalcemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Neonatal Bartter's syndrome is caused by mutations of NKCC2 or ROMK, classic Bartter's syndrome by mutations of ClC-Kb, Bartter's syndrome associated with sensorineural deafness is due to mutations of BSND, Gitelman's syndrome to mutations of NCCT and Bartter's syndrome associated with autosomal dominant hypocalcemia is linked to mutations of CASR.
|
15056980 |
2004 |
|
Congenital deafness
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
This might be due to a less severe loss of function of barttin induced by G47R mutation, compared with others, and our observation seems to suggest a possibility of the prevalence of mild form BSND with various levels of barttin dysfunction among patients with congenital deafness of unknown origin.
|
12574213 |
2003 |
|
Neoplasm Metastasis
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
In the present study, we quantified the plasma levels of EBV DNA/RNAs, such as LMP1, LMP2, BART and EBER1 with real-time quantitative PCR, and CTCs with a CellSpotter Analyzer in NPC patients, with or without metastasis.
|
31832991 |
2019 |
|
Primary malignant neoplasm
|
0.020 |
AlteredExpression
|
group |
BEFREE |
In NPC, miR-BARTs, the EBV-encoded miRNAs derived from BamH1-A rightward transcripts, are abundantly expressed and contribute to cancer development by targeting various cellular and viral genes.
|
29230817 |
2018 |
|
Primary malignant neoplasm
|
0.020 |
Biomarker
|
group |
BEFREE |
Accumulating evidence suggests that ebv-mir-BARTs play a critical role in host cell survival, immune escape, cell proliferation, cell apoptosis, and cancer metabolism, promoting the generation of NPC.
|
26909566 |
2017 |
|
Neoplasm Metastasis
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
Reconstitution of PTEN rescues all phenotypes generated by EBV-miR-BART1, highlighting the role of PTEN in EBV-miR-BART-driven metastasis in NPC.
|
26135619 |
2015 |
|
Epstein-Barr Virus Infections
|
0.020 |
Biomarker
|
group |
BEFREE |
Specifically, in nasopharyngeal carcinoma (NPC) tissues and the EBV-positive cell line C666-1, the miR-BART family accounted for more than 10% of all detected miRNAs, suggesting that these miRNAs have important roles in maintaining latent EBV infections and in driving NPC tumorigenesis.
|
24161012 |
2013 |
|
Epstein-Barr Virus Infections
|
0.020 |
AlteredExpression
|
group |
BEFREE |
In the present study, we proved that six forms of BARTs were present in EBV-positive cell lines and various tissue specimens with different EBV infection patterns.
|
22700548 |
2012 |
|
Essential Hypertension
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
We conclude that CLCNKB-T481S is associated with essential hypertension in males within the Ghanaian population; however, further studies are needed to understand its sex and ethnic segregation as well as to identify cellular factors that account for the divergent functional expression of ClC-Kb-T481S plus barttin in Xenopus oocytes and mammalian cells.
|
19226700 |
2009 |
|
Essential Hypertension
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Functional BSND variants in essential hypertension.
|
17954364 |
2007 |