AHNAK, AHNAK nucleoprotein, 79026

N. diseases: 60; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 Biomarker phenotype BEFREE These data indicate that CT694 is a novel T3S-dependent substrate unique to C. trachomatis, and that its interaction with host proteins such as AHNAK may be important for aspects of invasion or development particular to this species. 19460098 2009
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 Biomarker phenotype BEFREE Since AHNAK is involved in cell migration and invasion in other metastatic tumor cells, we conducted migration and invasion assays in mesothelioma cell lines. 24253341 2014
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 Biomarker phenotype BEFREE Overall, our data indicate the efficacy of FRAEM and reveal a role of TmeA during chlamydial invasion that manifests independently of effects on AHNAK. 28970272 2017
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 Biomarker phenotype BEFREE The role of AHNAK in cancer is however unclear as the protein has previously been described as a tumor suppressor, as well as being essential for tumor metastasis and invasion, while also being implicated in selected chemotherapeutic responses. 29309757 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 Biomarker phenotype BEFREE AHNAK suppresses tumour proliferation and invasion by targeting multiple pathways in triple-negative breast cancer. 28494797 2017
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 AlteredExpression phenotype BEFREE IMPLICATIONS: BRD4 functions as the dominant regulator of CRPC cell migration and invasion through direct transcriptional regulation of AHNAK, which together offer a novel targetable pathway to treat metastatic CRPC.<b>Visual Overview:</b> http://mcr.aacrjournals.org/content/molcanres/17/8/1627/F1.large.jpg. 31110158 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 AlteredExpression phenotype BEFREE Through over expression of AHNAK in both of U87 and U251, we demonstrated that overexpression of AHNAK could inhibit glioma cell proliferation and invasion, induce apoptosis, and inhibit in vivo glioma tumor growth and ki-67 expression. 28928883 2017