|
Hirschsprung Disease
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
On fluorescence microscopy, PGP 9.5, nNOS, and calretinin were significantly lower in the IAS of HD-mice than in C-mice (p < 0.05, respectively), while there were no significant differences between HD-mice and C-mice for S100, VIP, or TH.
|
30413921 |
2019 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Rectal suction biopsy with calretinin immunohistochemistry in patients suspected with residual aganglionosis after operation for Hirschsprung disease.
|
28341231 |
2017 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Unequivocal calretinin hypoinnervation was limited to the distal 2 cm, substantiating the warning of Kapur that small numbers of CRir nerves in the LP do not exclude a diagnosis of vsHD.
|
26230373 |
2016 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
The density and distribution of intramuscular neuronal nitric oxide synthase (nNOS)- and mucosal calretinin-immunoreactive nerves were evaluated proximal and distal to the anastomosis in redo resection specimens after pull-through surgery for Hirschsprung disease.
|
30915893 |
2019 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
ChT IHC was useful in unusual scenarios in which calretinin (CR) IHC failed to correctly identify patients with HSCR.
|
28649946 |
2019 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
To assess the diagnostic role of calretinin immunostaining in HD in comparison to neuron-specific enolase.
|
28139502 |
2017 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Calretinin immunostain was performed on 15 HD pull-through specimens, and multiple images were captured from the proximal aganglionic zone, TZ, and probable normal zone (NZ).
|
29304518 |
2019 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
At our institution, calretinin immunohistochemistry (CAL) is frequently requested by clinicians on rectal mucosal biopsies (RMBs) taken during colonoscopy in older children in whom suspicion for HD is low.
|
28508695 |
2019 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
The gradients of calretinin-stained pixel count increase per distance from the beginning of TZ (slope) for TCA were not significantly different from those for the conventional HD group.
|
31387515 |
2020 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
A significant difference between AM- and non-AM-affected tissues was found for calretinin (AM 0.55% vs. non-AM 1.44%) and MAP2 (AM 0.004% vs. non-AM 0.07%) staining measurements and software-based evaluations.
|
30175382 |
2019 |
|
Hirschsprung Disease
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The objectives of the current investigation were to evaluate the concordance of the results obtained by HE staining and the calretinin method with acetylcholinesterase (AChE) activity in fragments of mucosa and submucosa in the diagnosis of HD.
|
29212517 |
2017 |
|
Mesothelioma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Calretinin (CALB2) is a member of the EF-hand family of Ca(2+)-binding proteins and is expressed in a majority of poorly differentiated colon carcinoma and additionally in mesothelioma of the epithelioid and mixed type.
|
19998412 |
2010 |
|
Mesothelioma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Modulation of Calretinin Expression in Human Mesothelioma Cells Reveals the Implication of the FAK and Wnt Signaling Pathways in Conferring Chemoresistance towards Cisplatin.
|
31671889 |
2019 |
|
Mesothelioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Immunohistochemical markers for mesothelioma were positive for calretinin, cytokeratin AE1/AE3, and cytokeratin CAM5.2.
|
28463437 |
2017 |
|
Mesothelioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
To systematically investigate the sensitivity of calretinin and D2-40 antibodies in epithelioid and sarcomatoid areas of malignant mesotheliomas, a tissue microarray with 341 malignant mesotheliomas, including 112 epithelioid, 46 sarcomatoid and 183 biphasic tumors was constructed.
|
17361207 |
2007 |
|
Mesothelioma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The specificity of the effect was confirmed by stable enhanced green fluorescent protein-CR expression in mesothelioma cell lines and subsequent downregulation.
|
23595591 |
2013 |
|
Mesothelioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Calretinin (CR) is used as a positive marker for human malignant mesothelioma (MM) and is essential for mesothelioma cell growth/survival.
|
30555628 |
2018 |
|
Mesothelioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
It is suggested that calretinin is active in the first steps of carcinogenesis in all human mesotheliomas and during several stages in the evolution towards malignancy.
|
11299732 |
2001 |
|
Mesothelioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Immunocytochemical studies on PF cell blocks allow: (a) to distinguish mesothelioma from reactive mesothelial proliferations (e.g. loss of BAP1 nuclear expression, complemented by the demonstration of p16 deletion using fluorescence in situ hybridization, indicate mesothelioma); (b) to separate mesothelioma from adenocarcinoma (e.g. calretinin, CK 5/6, WT-1 and D2-40 are markers of mesothelioma, whereas CEA, EPCAM, TTF-1, napsin A, and claudin 4 are markers of carcinoma); and (c) to reveal tumor origin in pleural metastases of an unknown primary site (e.g.
|
30354850 |
2019 |
|
Mesothelioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Calretinin as a blood-based biomarker for mesothelioma.
|
28558669 |
2017 |
|
Mesothelioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
As calretinin and D2-40, the recognized positive markers of mesothelioma, are expressed in lung adenocarcinoma to some extent, novel markers with high specificity are desirable.
|
29327712 |
2018 |
|
Mesothelioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
There was positivity for vimentin, EMA, and cytokeratin 5/6 while WT1, calretinin, and CEA were negative; however, D2-40 showed diffuse membranous positivity in the epithelial areas and cytoplasmic positivity in the spindle areas confirming a mesothelioma.
|
21574263 |
2012 |
|
Mesothelioma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
(CK7 is common to all epithelial tumours, CEA can be expressed in clear cell carcinoma, WT1 is normally expressed in serous carcinoma, calretinin is expressed in mesothelioma and CK20 in colon carcinoma).
|
23265355 |
2013 |
|
Mesothelioma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Our aim was to elucidate mechanisms regulating calretinin expression in mesothelioma.
|
26848772 |
2016 |
|
Mesothelioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our findings demonstrate that the immunoreactivity observed in the mesotheliomas and their metastases investigated in this report is due to the concomitant presence of calretinin and the alternatively spliced form calretinin-22k.
|
15736446 |
2005 |