NEIL1, nei like DNA glycosylase 1, 79661

N. diseases: 59; N. variants: 5
Disease: Malignant Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.040 GeneticVariation group BEFREE We suggest that individuals who harbor the G83D NEIL1 variant face an increased risk for human cancer. 29156764 2017
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.040 AlteredExpression group BEFREE As a mechanism underlying the reduced expression of NEIL1 in cancer, the epigenetic silencing of NEIL1 through promoter hypermethylation was found. 27042257 2016
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.040 GeneticVariation group BEFREE In recent years, several genome and cancer single-nucleotide polymorphic variants of the NEIL1 glycosylase have been identified. 24382305 2014
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.040 GeneticVariation group BEFREE To date, only one reported study has investigated the association between NEIL1 and NEIL2 polymorphisms and cancer risk. 18594018 2008