Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0235653
Disease: Malignant neoplasm of female breast
Malignant neoplasm of female breast
0.040 Biomarker disease BEFREE These results add strength to the evidence showing that PALB2 is involved in BC risk for both sexes and indicate that consideration should be given to clinical testing of PALB2 for BRCA1/2 mutation-negative families with multiple MBC and FBC cases.Cancer 2017;123:210-218.© 2016 American Cancer Society. 27648926 2017
CUI: C0235653
Disease: Malignant neoplasm of female breast
Malignant neoplasm of female breast
0.040 GeneticVariation disease BEFREE Role of PALB2 Polymorphisms with Regard to Susceptibility to Female Breast Cancer Risk in the Chinese Population. 26981788 2016
CUI: C0235653
Disease: Malignant neoplasm of female breast
Malignant neoplasm of female breast
0.040 GeneticVariation disease BEFREE In the Finnish population, PALB2 (partner and localizer of BRCA2) represents a major susceptibility gene for female breast cancer, and so far, only one mutation has been described, c.1592delT, which leads to a sixfold increased disease risk. 26640152 2016
CUI: C0235653
Disease: Malignant neoplasm of female breast
Malignant neoplasm of female breast
0.040 GeneticVariation disease BEFREE In view of these similarities, we investigated whether the prevalence of PALB2 mutations was increased in breast cancer families with the occurrence of BRCA2 associated tumours other than female breast cancer. 20582465 2011