FZD3, frizzled class receptor 3, 7976

N. diseases: 39; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 GeneticVariation disease BEFREE The results indicate a potentially weaker effect of FZD3 polymorphisms on schizophrenia than that suggested originally and possibly limited to Chinese populations. 27755292 2016
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 Biomarker disease PSYGENET The present and previous findings indicated that genetic variants of the FZD3 gene may affect susceptibility to schizophrenia in Chinese Han and Va populations. 22027177 2011
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 GeneticVariation disease BEFREE The present and previous findings indicated that genetic variants of the FZD3 gene may affect susceptibility to schizophrenia in Chinese Han and Va populations. 22027177 2011
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 GeneticVariation disease BEFREE The results suggest that there may be interactive effects for schizophrenia among variants of the genes neuregulin 1 (NRG1, 8p22-p11), G72 (13q34), the regulator of G-protein signaling-4 (RGS4, 1q21-q22) and frizzled 3 (FZD3, 8p21). 18584117 2008
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 Biomarker disease PSYGENET FZD3 is unlikely to play a role in the genetic predisposition towards schizophrenia in the Caucasian population. 17982906 2007
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 GeneticVariation disease BEFREE FZD3 is unlikely to play a role in the genetic predisposition towards schizophrenia in the Caucasian population. 17982906 2007
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 Biomarker disease BEFREE Moreover, the meta-analytic result did not support the association between several commonly investigated markers in FZD3 and schizophrenia. 16707163 2006
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 Biomarker disease PSYGENET Moreover, the meta-analytic result did not support the association between several commonly investigated markers in FZD3 and schizophrenia. 16707163 2006
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 GeneticVariation disease BEFREE Association study of the frizzled-3 (FZD3) gene with schizophrenia and mood disorders. 15657645 2005
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 Biomarker disease PSYGENET Association study of the frizzled-3 (FZD3) gene with schizophrenia and mood disorders. 15657645 2005
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 GeneticVariation disease BEFREE Lack of a genetic association between the frizzled-3 gene and schizophrenia in a British population. 15288446 2004
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 Biomarker disease PSYGENET These results suggested that the FZD3 gene might be involved in the predisposition to schizophrenia. 15274031 2004
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 Biomarker disease BEFREE Although two prior studies have reported associations using limited numbers of SNPs on FZD3, our intensive study failed to support any major contribution of FZD3 to schizophrenia susceptibility. 15364045 2004
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 GeneticVariation disease BEFREE These results suggested that the FZD3 gene might be involved in the predisposition to schizophrenia. 15274031 2004
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 GeneticVariation disease LHGDN These results suggested that the FZD3 gene might be involved in the predisposition to schizophrenia. 15274031 2004
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 GeneticVariation disease LHGDN We found a significant association between schizophrenia and the FZD3 gene in single nucleotide polymorphisms and haplotype analyses. 14642436 2003
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 GeneticVariation disease BEFREE We found a significant association between schizophrenia and the FZD3 gene in single nucleotide polymorphisms and haplotype analyses. 14642436 2003
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 GeneticVariation disease BEFREE The global chi-squared test for haplotype transmission also showed a strong association (chi(2) = 48.84, df = 7, p <.000001).The strong association between the FZD3 locus and schizophrenia suggests that the gene itself may play a role in underlying schizophrenia, although a nearby gene responsible for predisposing to the illness cannot be ruled out. 14643098 2003