BICC1, BicC family RNA binding protein 1, 80114

N. diseases: 52; N. variants: 14
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022679
Disease: Cystic kidney
Cystic kidney
0.230 GeneticVariation disease BEFREE Several SAM-domain proteins that bind each other are mutated in patients with cystic kidneys or laterality defects, including the Ankyrin (ANK) and SAM domain-containing proteins ANKS6 and ANKS3, and the RNA-binding protein Bicc1. 29290488 2018
CUI: C0022679
Disease: Cystic kidney
Cystic kidney
0.230 Biomarker disease BEFREE Interestingly, Ofd1 and Bicc1 are both involved in renal cystogenesis and selected targets were shown to accumulate in two models of inherited renal cystic disease. 28450740 2017
CUI: C0022679
Disease: Cystic kidney
Cystic kidney
0.230 AlteredExpression disease BEFREE We show that cAMP and the expression of its synthetic enzyme adenylate cyclase-6 (AC6) are up-regulated in cystic kidneys of Bicc1(-)(/-) knockout mice. 22641646 2012
CUI: C0022679
Disease: Cystic kidney
Cystic kidney
0.230 Biomarker disease MGD