ADAM33, ADAM metallopeptidase domain 33, 80332

N. diseases: 49; N. variants: 22
Disease: Allergic bronchitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1260881
Disease: Allergic bronchitis
Allergic bronchitis 		0.010 GeneticVariation disease BEFREE Multiple associations were observed for ADAM33: rs2280090 was associated with reduced MEF240% (i.e., the ratio of Mean Expiratory Flow after 240s of hypertonic saline inhalation with respect to the age- and ancestry-matched reference value) and with an increased risk of allergic bronchitis (p = 1.77*10(-4) and p = 7.94*10(-4), respectively); rs3918396 was associated with wheezing and eczema comorbidity (p = 3.41*10(-4)). 27624002 2016