ADAM33, ADAM metallopeptidase domain 33, 80332

N. diseases: 49; N. variants: 22
Disease: IgE-mediated allergic asthma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1827849
Disease: IgE-mediated allergic asthma
IgE-mediated allergic asthma 		0.030 GeneticVariation disease BEFREE To verify the association of transforming growth factor-beta1(TGF-beta1) (C-509T and T869C), CD14 (C-159T), IL-4 (C-590T), IL-4R (ILe50Val) and ADAM33 (S_2) gene polymorphisms with asthma severity in a sample of patients with mild, moderate and severe persistent atopic asthma. 18425216 2008
CUI: C1827849
Disease: IgE-mediated allergic asthma
IgE-mediated allergic asthma 		0.030 Biomarker disease BEFREE Twenty-three ADAM33 SNPs were genotyped by fluorescence correlation spectroscopy with the use of DNA from 155 families (538 members) identified through children with atopic asthma. 16650044 2006
CUI: C1827849
Disease: IgE-mediated allergic asthma
IgE-mediated allergic asthma 		0.030 GeneticVariation disease BEFREE However, our data may suggest a complex role of ADAM33 polymorphisms in asthma ethiology, especially in non atopic asthma. 16784537 2006