CLPTM1L, CLPTM1 like, 81037

N. diseases: 110; N. variants: 20
Disease: Lung Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.330 Biomarker group CTD_human CLPTM1L expression was required in vitro for morphologic transformation by H-RasV12 or K-RasV12, anchorage-independent growth, and survival of anoikis of lung tumor cells. 24366883 2014
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.330 AlteredExpression group BEFREE CLPTM1L expression was required in vitro for morphologic transformation by H-RasV12 or K-RasV12, anchorage-independent growth, and survival of anoikis of lung tumor cells. 24366883 2014
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.330 Biomarker group BEFREE Upon loss of CLPTM1L accumulation in lung tumor cells, cisplatin and camptothecin induced apoptosis were increased in direct proportion to the level of CLPTM1L knockdown. 22675468 2012
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.330 Biomarker group CTD_human Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. 19151717 2009
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.330 Biomarker group CTD_human Common 5p15.33 and 6p21.33 variants influence lung cancer risk. 18978787 2008
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.330 Biomarker group LHGDN Lung cancer susceptibility locus at 5p15.33. 18978790 2008