Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.310 GeneticVariation disease BEFREE To translate the rodent findings to human conditions, several CAMK2A gene polymorphisms were tested regarding their risk for a fast establishment of cocaine dependence in two independent samples of regular cocaine users from Brazil (n=688) and Switzerland (n=141). 25290264 2014
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.310 Biomarker disease CTD_human Suppressing calcium/calmodulin-dependent protein kinase II activity in the ventral tegmental area enhances the acute behavioural response to cocaine but attenuates the initiation of cocaine-induced behavioural sensitization in rats. 14725635 2004