KLRC4, killer cell lectin like receptor C4, 8302

N. diseases: 82; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.630 GeneticVariation disease BEFREE Six SNPs (in decreasing order of significance, rs7616215 located 38 kb downstream of CCR1, rs2617170 [rs2617170;rs281860419" genes_norm="3107;8302">p.Asn104Ser] in KLRC4, rs17810546 in IL12A-AS1, rs7574070 in STAT4, and rs10050860 [rs10050860" genes_norm="51752">p.Asp575Asn] and rs13154629 in ERAP1) were nominally associated with BD in both allelic association tests (5.05 × 10(-9) ≤ Pallele ≤ 7.55 × 10(-3) ) and sex-adjusted genotypic association tests (6.01 × 10(-9) ≤ adjusted P value ≤ 1.30 × 10(-2) ). 26097239 2015
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.630 SusceptibilityMutation disease ORPHANET Brief report: association of CCR1, KLRC4, IL12A-AS1, STAT4, and ERAP1 With Behçet's disease in Iranians. 26097239 2015
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.630 GeneticVariation disease BEFREE Our study demonstrates that the MBL2/rs1800450 and KLRC4/rs2617170 are susceptibility factors for BD in a Chinese Han population. 28706259 2017
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.630 Biomarker disease CTD_human Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1. 23291587 2013
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.630 GeneticVariation disease GWASCAT Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1. 23291587 2013
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.630 GeneticVariation disease GWASDB Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1. 23291587 2013
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.630 Biomarker disease BEFREE In the current study of Behçet disease (BD), nonsynonymous variants (NSVs) identified by deep exonic resequencing of 10 genes found by GWAS (IL10, IL23R, CCR1, STAT4, KLRK1, KLRC1, KLRC2, KLRC3, KLRC4, and ERAP1) and 11 genes selected for their role in innate immunity (IL1B, IL1R1, IL1RN, NLRP3, MEFV, TNFRSF1A, PSTPIP1, CASP1, PYCARD, NOD2, and TLR4) were evaluated for BD association. 23633568 2013
CUI: C0023434
Disease: Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia 		0.300 Biomarker disease CTD_human Scan of 977 nonsynonymous SNPs in CLL4 trial patients for the identification of genetic variants influencing prognosis. 18006695 2008
CUI: C0003123
Disease: Anorexia
Anorexia 		0.100 Biomarker disease HPO
CUI: C0003504
Disease: Aortic Valve Insufficiency
Aortic Valve Insufficiency 		0.100 Biomarker disease HPO
CUI: C0003864
Disease: Arthritis
Arthritis 		0.100 Biomarker disease HPO
CUI: C0014038
Disease: Encephalitis
Encephalitis 		0.100 Biomarker disease HPO
CUI: C0014118
Disease: Endocarditis
Endocarditis 		0.100 Biomarker disease HPO
CUI: C0017086
Disease: Gangrene
Gangrene 		0.100 Biomarker disease HPO
CUI: C0022575
Disease: Keratoconjunctivitis Sicca
Keratoconjunctivitis Sicca 		0.100 Biomarker disease HPO
CUI: C0025289
Disease: Meningitis
Meningitis 		0.100 Biomarker disease HPO
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.100 Biomarker disease HPO
CUI: C0027121
Disease: Myositis
Myositis 		0.100 Biomarker disease HPO
CUI: C0030305
Disease: Pancreatitis
Pancreatitis 		0.100 Biomarker disease HPO
CUI: C0031046
Disease: Pericarditis
Pericarditis 		0.100 Biomarker disease HPO
CUI: C0032231
Disease: Pleurisy
Pleurisy 		0.100 Biomarker disease HPO
CUI: C0034065
Disease: Pulmonary Embolism
Pulmonary Embolism 		0.100 Biomarker disease HPO
CUI: C0042384
Disease: Vasculitis
Vasculitis 		0.100 Biomarker disease HPO
CUI: C0085582
Disease: Retrobulbar Neuritis
Retrobulbar Neuritis 		0.100 Biomarker disease HPO
CUI: C0086543
Disease: Cataract
Cataract 		0.100 Biomarker disease HPO