|
Sore to touch
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
Out of these, the LD-block 3 in calpastatin, tagged by SNPs located at 7-98566391 and 7-98581038, had a significant effect on tenderness with the TG-CG diplotype being approximately 1 kg more tender than the toughest diplotype, TG-CG.
|
29520298 |
2018 |
|
Sore to touch
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
Single nucleotide polymorphisms (SNPs) carried in calpain (CAPN1), calpastatin (CAST), and leptin (LEP) genes are associated with meat tenderness.
|
28525658 |
2017 |
|
Sore to touch
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The micromolar calcium activated neutral protease <i>(CAPN1)</i> and calpastatin <i>(CAST)</i> have been widely regarded as genes related to muscle growth and meat tenderness.
|
28713829 |
2017 |
|
Sore to touch
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Meat tenderness and inhibitory activity of calpastatin may be associated with divergent temperament indices in zebu cattle.
|
28759886 |
2017 |
|
Sore to touch
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
Combining beef cattle data identified correlated SNPs representing CAPN1 (chr29:44 M+) and CAST (chr 7:96 M+) loci affecting beef tenderness, showing pleiotropic effects in dairy cattle.
|
28835686 |
2017 |
|
Sore to touch
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
The objectives of this study were to characterize the allelic and genotypic frequencies of polymorphisms in the µ-calpain and calpastatin genes, and to assess their association with meat tenderness and animal growth in Nellore cattle.
|
28218779 |
2017 |
|
Sore to touch
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
In conclusion, ZH supplementation improved hypertrophy, meat production, and debone yield in Nellore heifers, which led to decreased tenderness and to increased mRNA expression in the calpain-calpastatin system.
|
27427783 |
2016 |
|
Sore to touch
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
The CAPN1:c.1589G>A (Val530Ile) SNP marker displayed significant effect on the meat tenderness score which is strongly supported by molecular modeling of the CAPN1:c.1589G>A (Val530Ile) variant that inhibits CAST protein from binding more strongly than the wild-type protein, which may explain its effect on meat tenderness.
|
24468663 |
2014 |
|
Sore to touch
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
Two favorable CAST alleles increased tenderness ratings of AT-striploin, TS-striploin, rump, and oyster blade steaks by, respectively, 6.1, 4.2, 4.2, and 3.1 units, and overall liking by 4.7, 2.8, 2.9, 3.7 (all P < 0.04).
|
22367069 |
2012 |
|
Sore to touch
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The eight SNP, which were located within five genes: mu-calpain (CAPN1), calpastatin (CAST), leptin (LEP), growth hormone receptor (GHR) and acylCoA:diacylglycerol acyltransferase 1 (DGAT1), are included in various commercial tests for tenderness, fatness, carcass composition and milk yield/quality.
|
19555501 |
2009 |
|
Sore to touch
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Younger slaughter age and lower calpastatin activity both resulted in greater tenderness (P < .05).
|
8707712 |
1996 |