EOMES, eomesodermin, 8320

N. diseases: 60; N. variants: 2
Disease: Promyelocytic leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2745900
Disease: Promyelocytic leukemia
Promyelocytic leukemia 		0.020 AlteredExpression disease BEFREE In addition, under steady-state conditions, DP T cells expressed eomesodermin (Eomes) and promyelocytic leukemia zinc finger (PLZF) proteins, both of which act as transcription factors in innate/memory-like T cells. 30116750 2018
CUI: C2745900
Disease: Promyelocytic leukemia
Promyelocytic leukemia 		0.020 AlteredExpression disease BEFREE Among these, CD56, CD84, and CD94 defined a subset with higher expression of the transcription factors promyelocytic leukemia zinc finger (PLZF), eomesodermin, and T-bet and enhanced capacity to respond to IL-12 and IL-18 stimulation. 28630305 2017