Septicemia
|
0.400 |
Biomarker
|
disease |
BEFREE |
In addition, PER administration also decreased the lung tissue NF-κB and Caspase-3 immunopositivity against sepsis.
|
31733315 |
2020 |
Septicemia
|
0.400 |
Biomarker
|
disease |
BEFREE |
The expression of α7nAChR, toll-like receptor 4 (TLR4), high mobility group box 1 (HMGB1), and cleaved caspase-3 increased, peaking 24 h during sepsis.
|
31520992 |
2019 |
Septicemia
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Western blot and quantitative real time-polymerase chain reaction (qRT-PCR) were conducted to detect the protein and mRNA expression levels of LC3, Beclin-1, activated caspase-3, p-Akt (308), p-Akt (472), Akt and NKILA in kidney tissues of sepsis rats at different time points, respectively.
|
31599426 |
2019 |
Septicemia
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The effect may be mediated by up-regulation of survivin via activation of NF-κB, which leads to reduced activation of caspase-3 and consequent apoptosis of cardiomyocytes in experimental sepsis.
|
30279549 |
2018 |
Septicemia
|
0.400 |
Biomarker
|
disease |
BEFREE |
Following sepsis induction, diagnosis, the brains were analyzed for both function and ultrastructural morphology.We determined that IAH exacerbated sepsis induces sepsis-associated encephalopathy when examining low score of neurological function and more delta wave in EEG, increased neuronal edema in LPS + IAH group, as well as an escalation of Bax and Cleaved-caspase-3, Cleaved-parp, and reduction of Bcl-2 and Mfsd2a in LPS + IAH group.
|
29802336 |
2018 |
Septicemia
|
0.400 |
Biomarker
|
disease |
BEFREE |
Sepsis acutely increased apoptosis (increased caspase-3 and PARP cleavage), autophagosome formation (increased LC3B-II), and canonical inflammasome activity (increased NLRP3, TMS1, cleaved caspase-1).
|
29240643 |
2018 |
Septicemia
|
0.400 |
Biomarker
|
disease |
BEFREE |
Sevoflurane exerts brain-protective effects against sepsis-associated encephalopathy and memory impairment through caspase 3/9 and Bax/Bcl signaling pathway in a rat model of sepsis.
|
29756489 |
2018 |
Septicemia
|
0.400 |
Biomarker
|
disease |
BEFREE |
The percentage of the immunostained positive area in the spiral ligament significantly correlated with the grade of hearing loss for BAX (<i>P</i>=0.027) and Cleaved-caspase 3 (<i>P</i>=0.024) but not for BCL 2 (<i>P</i>>0.05).The present data suggests that severe, non-lethal sepsis in mice results in significantly elevated hearing thresholds.
|
28404559 |
2017 |
Septicemia
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Besides, we detected the increasing expression level of Caspase-3 and increasing ratio of TUNEL positive cells in the thyroid after sepsis.
|
27521250 |
2016 |
Septicemia
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In this study, we investigated the prognostic value of cfDNA in patients with sepsis and its possible correlation with caspase-3, IL-6 and IL-18 levels.
|
26960212 |
2016 |
Septicemia
|
0.400 |
Biomarker
|
disease |
CTD_human |
Effect of chemically modified tetracycline on transforming growth factor-beta1 and caspase-3 activation in liver of septic rats.
|
16003065 |
2005 |