Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
0.040 Biomarker group BEFREE Here, we show that <i>Drosophila</i> l(3)mbt brain tumors are more invasive and develop as malignant neoplasms more often in males than in females. 31453329 2019
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
0.040 AlteredExpression group BEFREE Here, we have meta-analyzed gene expression profiles of the human orthologs of Drosophila melanogaster germline genes that are ectopically expressed in l(3)mbt brain tumors using gene expression datasets derived from a large cohort of human tumors. 24243547 2014
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
0.040 Biomarker group BEFREE We demonstrate that brain tumours in l(3)mbt mutants originate from overproliferation of neuroepithelial cells in the optic lobes caused by derepression of target genes in the Salvador-Warts-Hippo (SWH) pathway. 21857667 2011
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
0.040 GeneticVariation group BEFREE Homozygous mutations in the l(3)mbt gene cause brain tumors in Drosophila, identifying l(3)mbt as a tumor suppressor gene. 12588862 2003